Stroke Flashcards

1
Q

Define stroke.

A

A neurological deficit of sudden onset, lasting more than 24 hours and of vascular origin.

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2
Q

Can a stroke last less than 24 hours?

A

No, this would be a TIA.

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3
Q

What are the symptoms of stroke?

A
Loss of power
Loss of sensation
Loss of speech
Loss of vision
Loss of co-ordination

–> Stroke symptoms are loss of function

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4
Q

What would likely be found on examination/taking a neurological history?

A

Motor: clumsy or weak
Sensory: loss of feeling
Speech: dysartrhia or dysphagia
Vision problems

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5
Q

What is a stroke?

A

Ischaemic: damage to part of the brain due to blockage of a blood vessel by a thrombus or embolus –> 85%

Haemorrhagic: damage to part of the brain by rupture of a blood vessel –> 15%

Also, disease of vessel wall and disturbance of normal properties of blood.

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6
Q

Which vessels supply the brain?

A

4 vessels go to the brain - 2 vertebral arteries and 2 common carotid arteries. 2 vertebral arteries join to form the basilar artery –> divide to form 2 posterior cerebral arteries. 2 common carotid become internal carotid then middle cerebral –> this is the most common place for a clot to lodge.

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7
Q

If a patient is unable to speak, which part of the brain is probably involved?

A

Large part as speech is spread across the brain –> this is more serious.

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8
Q

Define homunculus.

A

A physical representation of the human body located within the brain.

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9
Q

What would happen if a stroke occurs in deep white matter?

A

Major deficit as fibres are packed close together.

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10
Q

What are the different types of ischaemic stroke?

A

Clot stops blood supply to an area of the brain.

  • Large artery atherosclerosis - carotid stenosis (most common)
  • Cardioembolic (due to AF, worse than other types)
  • Small artery occlusion
  • Arterial dissection
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11
Q

What are the different types of haemorrhagic stroke?

A

Primary intercerebral haemorrhage –> 70%.

Secondary haemorrhage –> 30% (subarachnoid)

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12
Q

What are the 4 stroke subtypes?

A

1) TACS: total anterior circulation (20%); higher cerebral dysfunction; weakness; sensory deficit; homonymous hemianopia; large strokes; 6% mortality and recurrence at 1 year
2) PACS: partial anterior circulation (35%); 2/3 of TACS criteria or restricted motor/sensory deficit; more restricted cortical infarcts; 16% mortality at 1 year and 17% recurrence
3) LACS: lacunar (20%); silent and underdiagnosed; pure motor; pure sensory; or combination; ataxia hemiparesis (weakness more prominent in leg than arm); 11% mortality and 9% recurrence
4) POCS: posterior circulation (25%); affect brainstem, cerebellar or occipital lobes; complex presentation; 19% mortality 1 year and 20% recurrence

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13
Q

What is homonymous hemianopia?

A

Loss of part of the field of view on the same side in both eyes - due to left cerebrovascular events (STROKE).

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14
Q

What are modifiable risk factors for stroke?

A

AF and HT

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15
Q

What are non-modifiable risk factors for stroke?

A

Age, race and FH.

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16
Q

What are the investigations of stroke?

A

Bloods, ECG, imaging (CT, MRI, Doppler). CT best for haemorrhagic. MRI best for ischaemic.

17
Q

What is the only approved treatment for ischaemic stroke?

A

TPA - tissue plasminogen factor. Improved blood flow to part of brain being deprived.