Stroke Flashcards

1
Q

what is an ischaemic stroke

A

blocked artery reducing blood flow to brain

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2
Q

Most common type of stroke

A

Ischaemic

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3
Q

Damage from ischaemic stroke ..

A

dependant on location of blockage and how long suffers

IE if self resolves in 24 hours it is a TIA

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4
Q

Two causes of ischaemic stroke

A
  1. endothelial cell dysfunction- inflamed of irritated endothelium- tunica intica
    irritants (smoking) cause formation of atherosclerosis causing obstruction after -plaques dislodging exposing thrombogenic core which then form clots
  2. embolism - blood clot breaks off and then gets lodged in an artery downstream (if in heart will be in left side of heart unless atrial septal defect)
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5
Q

common areas for brain atherosclerosis formation are

A

branch areas
particularly internal carotid and middle cerebral
there usually take years to form

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6
Q

epidemiology of strokes

A

110000 people have strokes
uncommon under 40
males> females
incidence falling due to primary care - statins and bp checks

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7
Q

Causes of ischaemic stroke

A
atherosclerosis
large artery stenosis
cardiac emboli from AF, MI or infective endocarditis  causing blood stasis
shock- reduced blood flow
vasculitis
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8
Q

Risk factors

A
Male 
black or Asian
hypertension
smoking
age
previous TIA
alcohol
heart disease 
atrial fibrillation
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9
Q

signs of stroke

A

slurred speech
arm/leg weakness
facial dropping
act FAST

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10
Q

symptoms dependant on location

MCA- middle cerebral artery

A

provides to temporal mostly
contralateral motor weakness- arms and legs
hemiplegia - paralysis of one side of body
contralateral sensory loss
aphasia- can understand (wernickes) or produce speech (brocas)
dysphagia- speech problems if in dominant hemisphere
facial droop

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11
Q

symptoms depend on location

ACA - anterior cerebral artery infarction

A

frontal
contralateral weakness and sensory loss of lower limb
truncal ataxia- wide drunken gait - uncertain steps, lateral deviations and unequal steps
incontinence
drowsiness
logical thinking
personality

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12
Q

symptoms depend on location

PCA- posterior cerebral artery infarction

A

occipital
disorders of perception
contralateral homonymous hemianopia - ie cant see on right side in both eyes

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13
Q

symptoms depend on location

vertebrobasilar artery - more catastrophic that PCA as more areas are supplied

A

disorders of balance

coordination disorders

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14
Q

symptoms depend on location

cerebral hemisphere infarction

A

most common infarction of internal capsule following occlusion of a branch from MCA
weakness and paralysis of one side
aphasia
cognitive impairments

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15
Q

symptoms depend on location

brainstem infarction

A

lateral medullary syndrome
caused by occlusion of posterior inferior cerebellar artery
sudden vomiting
vertigo
ipsilateral horners syndrome - hypohydrosis facial numbness dysarthria limb ataxia and dysphagia
contralateral loss of pain and temp sensation

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16
Q

investigations for suspected stroke

A
head CT
MRI 
- to rule out bleed 
CT angiography 
echocardiography- suspected cardioembolic stroke
pulse ecg and BP- look for AF
bloods:
FBC- thrombocytopenia and polycythaemia
blood glucose- rule out hypoglycemia
coag test
17
Q

treatement for ischaemic stroke

A

thrombolysis - IV alteplase
- tissue plasminogen activation
contraindications- haemorrhage, intercranial bleed, clotting disorders
asprin for 2 weeks then clopidogrel

18
Q

treatment for haemorrhagic stroke

A

control BP-beta blockers or ARB
beriplex or vit K if warfarin related
surgery clot evasion

19
Q

management after stroke

A
stop smoking
less alcohol
diet
exercise 
rehabilitation - physio and OT
20
Q

what is a haemorrhagic stroke

A

bleeding from a single vessel within the brain caused by high blood pressure commonly

21
Q

cause of haemorrhagic stroke

A
trauma
aneurysm rupture 
anticoagulation
thrombolysis
carotid artery dissection
artherothromboembolism
vasculitis
21
Q

cause of haemorrhagic stroke

A
trauma
aneurysm rupture 
anticoagulation
thrombolysis
carotid artery dissection
artherothromboembolism
vasculitis
22
Q

the differential diagnosis for stroke

A

hypoglycemia
labyrinthine disorders- labyrinthitis/vestibular neuronitis, BPPV, Meniere’s disease
migrainous aura - typical visual and sensory symptoms and dysphagia as well as motor weakness
mass lesions - subdural haematoma cerebral abscess or tumours
postictal weakness
syncope due to arrhythmia
simple partial seizures
functional hemiparesis