Streptococcal B infection

Question 1

Giving the patient’s age and non specific findings a suggestive respiratory process should have what other possible differentials? What type of treatment should be considered?

Answer 1

Urinary tract infection, CSF infection, or generalized sepsis. Empiric antibiotics

Question 2

What is the most common cause of the infection for a six day old child?

Answer 2

E. coli and Group B strep infections; Streptococcus pneumonia, group B strep, Haemophilus, listeria, anaerobes

Question 3

What is the only indication for respiratory infection for infants?

Answer 3

Tachypnea which can be missed. Often times these young infants do not have typical rales or sounds of consolidation on auscultation

Question 4

What are the differential considerations for infants in the first 24 to 48 hours of life exhibit respiratory symptoms?

Answer 4

Hyaline membrane disease and transient tachypnea

Question 5

Is GBS infection screening 100% sensitive for the mother? Is it still possible that the infant can have group B strep infection after the mother has received intrapartum antibiotics?

Answer 5

No and yes

Question 6

What will grow the offending organism in newborn with respiratory illness?

Answer 6

Blood cultures or frequently grow offending organism

Question 7

When she did Empiric antibiotic coverage be given?

Answer 7

As soon as possible AFTER culture fluids are obtained

Question 8

What is that in Empiric antibiotic that should be given to newborns with respiratory symptoms?

Answer 8

Ampicillin 100 mg/kg/d divided every 12 hours if less than 1.2 kg or every eight hours for infants who are greater than 1.2 kg
Cefotaxime (Claforan) 100 mg/kg/d Divided every 12 hours or 150 divided every eight hours if greater than 1.2 kg or greater than 1 week old
Gentamicin can be added or use as an alternative treatment when there is no evidence of meningitis