STR Loci And Kinship

Question 1

What is an STR?

Answer 1

A short tandem repeat

Question 2

What do you need to estimate the correct frequency of the profile in the right population is critical

Answer 2

• allele frequencies from the population from the population database
• the database to be in the HW equilibrium
• no linkage disequilibrium between loci
• locus is not selected for or against (selectively neutral)

Question 3

Define prior probability

Answer 3

The prior probability assigned before any testing

Question 4

Define posterior probability

Answer 4

The revised probability that the person has the disease in light of additional information obtained about the test results.

Question 5

What is the odds form of bayes law?

Answer 5

Posterior odds = likelihood ratio x prior odds