Stones Flashcards
name five diseases that are risk factors for stones
hyperparathyroidism
RTA
Obesity
Gout Diabetes
if you have recurrent stones what two things are you at risk for?
osteoporosis and ostiopenia
what are the three steps in stone formation?
supersaturation
nucleation
aggregation
what is the most common type of stone?
calcium oxalate
how does caclium oxalate appear on Xray?
opaque
how does calcium phosphate appear on Xray?
opaque
how does magnesium ammonium phosphate or struvite appear on Xray?
opque
how does uric acid stone appear on Xray?
lucent
how does cystine stone appear on Xray?
opaque
what is the usual cause of a calcium oxalate stone?
idiopathic hypercalcemia
where do nuclei commonly bind to when forming a calcium oxalate stone?
an area called randalls plaque
where is randalls plaque? why is it important?
in the terminal collecting duct and minor calyx…it is a spot for nucleation to occur in calcium oxalate stones…they attach and grow here until they break off
what two things must be high in the urine to have a calcium oxalate stone?
oxalate and calcium
what usually is cause of hyperoxaluria?
high dietary intake
does high or low uric acid lead to a risk for calcium oxalate stones?
high…because they block the inhibitors of stones like citrate
what must patients have to have a calcium phosphate stone?
high urine pH or basic pH
where do struvite or magnesium ammonium stones come from?
infections
what must an organism have to cause a struvite stone?
urease
name the three common infections leading to struvite stones, which is most common?
proteus..most common
staphylococcus
Klebsiella
how do you treat a struvite stone?
have to remove the whole thing surgically
what are two risks with struvite stones?
renal failure and sepsis
if you eat a ton of read meat…what type of stone are you likely to have? why?
uric acid stone
uric acid is breakdown product of purines
what is the rule about uric acid stones and pH of urine?
to have a uric acid stone the urine pH must be lower than 5.5
name the only stone that has a genetic link? what is the genetics?
cystine stones
auto recess