STI Study Guide

Question 1

1st Line Tx for Chlamydia

Answer 1

Azithromycin 1g x 1 OR Doxy 100 mg x 7 d

Question 2

Alternative Tx for Chlamydia

Answer 2

Erythromycin or Levofloxacin

Question 3

Chlamydia Tx Recommended in Pregnancy

Answer 3

Azithromycin 1g x 1; or Amoxil 1g x 1; or Amoxil 500mg TID x 7d

Question 4

1st Line Gonorrhea Tx

Answer 4

Ceftriaxone 250mg IM x 1 & tx for Chlamydia

Question 5

1st Line Syphillis Tx (T. pallidum)

Answer 5

IM benzathine PCN G 2.4 million units x 1

Question 6

Alternative Tx for Syphillis

Answer 6

Doxy 100mg BID x 14d

Question 7

Follow up for Syphillis

Answer 7

Re-examine at 6, 12, & 24 mo post tx

Question 8

Tx for Trichomoniasis

Answer 8

Metronidazole (Flagyl) 2g x 1 or 500mg BID x 7d

Question 9

Metronidazole (Flagyl) Contraindication

Answer 9

Avoid ETOH during tx and 24 hr after last dose!!!

Question 10

Genital Wart Tx (Patient Application)

Answer 10

Podofilox (Condylox); Imiquimod (Aldara)

Question 11

Genital Wart Tx (Physician Application)

Answer 11

Podophyllin Resin

Question 12

Podofilox (Condylox) Tx Length

Answer 12

Until no visible warts; Use for a max of 4 wks

Question 13

Imiquimod (Aldara) Tx Length

Answer 13

At bedtime for up to 16 wks

Question 14

Podofilox (Condylox) Contraindications

Answer 14

During pregnancy; Not recommended for vaginal or anal use

Question 15

Podophyllin Resin AE

Answer 15

Neurotoxicity

Question 16

1st Line Episodic Tx of HSV

Answer 16

Valacyclovir 1 g BID x 7-10d

Question 17

1st Line Suppressive Tx of HSV

Answer 17

Valacyclovir 500mg QD

Question 18

1st Line Bacterial Vaginosis Tx

Answer 18

Metronidazole (Flagyl) 500 mg PO x 7 d; or Metronidazole gel intravaginally QD x 5d; or Clindamycin crm intravaginally QD x 7d

Question 19

Common PID pathogens

Answer 19

C. trachomatis or N. gonorrhoeae

Question 20

IV PID Tx

Answer 20

Cefotetan IV BID & Doxy PO BID x 14 d; or Clindmycin IV TID & Gentamicin x 14 d

Question 21

Outpatient PID Tx

Answer 21

Ceftriaxone 250mg IM & Doxy +/- Flagyl x 14 d

Question 22

IV Azithromycin Side Effects

Answer 22

Arrhythmias; Hearing disturbances; Dizzy; HA; convulsions

Question 23

IV Azithromycin Contraindications

Answer 23

Hepatic dysfunction; QT prolongation

Question 24

IV Azithromycin Drug Interactions

Answer 24

Warfarin augmented by azithro

Question 25

IV Doxy Side Effects

Answer 25

Dental discoloration (gray teeth)

Question 26

IV Doxy Drug Interactions

Answer 26

Decrease effectiveness of other ABX

Question 27

Doxy Pregnancy Category

Answer 27

D

Question 28

IM/IV PCN G Contraindications

Answer 28

Renal impairment; C. diff associated w/ diarrhea

Question 29

IM/IV Ceftriaxone Side Effects

Answer 29

Immune mediated hemolytic anemia

Question 30

PO/IV/Topical Metronidazole Side Effects

Answer 30

Stevens-Johnsons syndrome

Question 31

PO/IV/Topical Metronidazole Contraindications

Answer 31

Use in 1st trimester; ETOH use during tx

Question 32

PO/IV/Topical Metronidazole Drug Interactions

Answer 32

ETOH

Question 33

Valacyclovir Contraindications

Answer 33

Caution in HIV therapy d/t risk of TTP & hemolytic uremic syndrome; In elderly watch for acute renal failure

Question 34

Valacyclovir Drug Interactions

Answer 34

Use with Bacitracin (nephrotoxic/ototoxic effect); With Cimetidine (increases Valtrex levels d/t decreased renal clearance)

Question 35

PO/IM/IV/Topical Clindamycin Side Effects

Answer 35

Stevens-Johnsons syndrome

Question 36

PO/IM/IV/Topical Clindamycin Drug Interactions

Answer 36

Increases Warfarin effect; PO increases digoxin levels