STI's Flashcards
What are the different ways that gonorrhea can present?
Urethritis (males), urogenital infection (women), and Opthalmia neonatorum (babies)
In general: dysuria, discharge, abdominal pain
How do we detect gonorrhea?
NAAT
Vaginal swab
how do you treat gonorrhea?
*resistance to antibiotic is the hallmark of GC
Ceftriaxone 250mg IM single dose PLUS Azith 1 gram
OR
Doxycycline 100mg BID x 7 days
What should we always do after we after treatment for gonorrhea?
Re-test for cure in 3 months
Chlamydia can also present in men, women, and babies as asymptomatic, discharge, or painful. How do we test for it?
NAAT – URINE for men
NAAT – VAGINAL swab for women
Can also do tissue culture SWAB followed with an enzyme immunoassay (EIA)
How do we treat chlamydia?
Azithromycin 1g x 7 days
OR
Doxy 100mg BID x 7 days
What should we do after treatment for chlamydia?
Test for cure is NOT advised (except in preggo women; if done do after 3-4 weeks, concern for false +)
A pt presents with pruritus and malodorous discharge, dx? What will you see on PE?
Trichomonas
PE: vaginal and cervix erythema, + wiff test with wet mount showing motile flagellates
How do you treat trich?
Metronidazole
*Treat all partners
What causes syphilis?
Treponema pallidum (corkscrew shaped)
how does syphilis transmit?
direct contact with syphilis chancre during primary and secondary stages
What are the 3 stages of syphilis, what are the sxs associated with each?
Primary – Chancer at sit of inoculation, painless, becomes systemic within 30 hours
Secondary – weeks to months later rash (MC), fever, HA, malaise, diffuse LAD
Tertiary – from 1-30 years, ASX or Gummas (nodular lesions on skin & bones), CV (aortitis, aortic aneurysm, and aortic regurg)
Neurosyphillis – Insanity (personality change, sensory deficits, Argyll-roberston pupils), tabes dorsalis (shuffling gate), ophthalmic involvement
When is a person with syphilis infectious?
Primary and Secondary
Less than 1 year = Early Latent – Asx, detectable with serologic testing, still infectious
Greater than 1 year = Late Latent – Asx, not infectious, requires longer treatment
How do you diagnose syphilis?
Darkfield microscopy (direct vizulization of spirochete from chancre, rarely used in general practice)
Serologic – Nontreponeal test (screening or confirm success of treatment) or Treponemal (Detect antiobdies)
PCR – High sensitivity and specificity (not used in practice thus far)
How do you treat primary, secondary, or early latent syphilis?
PCN 2.4 million units IM
Or Doxy