STI Pharmacology Quiz

Question 1

Chlamydia trachomatis classification

Answer 1

Intracellular gram negative organism

Question 2

Neisseria gonorrhoeae classification

Answer 2

Gram negative diplococci

Question 3

Trichomonas vaginalis classification

Answer 3

Flagellated protozoa

Question 4

Treponema pallidum classification

Answer 4

Gram negative spirochete

Question 5

Garderella vaginalis classification

Answer 5

Anaerobic coccobacilli

Question 6

Chlamydia trachomatis treatment of choice

Answer 6

Doxycycline 100 mg BID PO x7 days (alternative azithromycin 1 g PO once)

Question 7

Neisseria gonorrhoeae treatment of choice

Answer 7

Ceftriaxone 500mg IM x1 PLUS chlamydia coverage

Question 8

Trichomonas vaginalis treatment of choice

Answer 8

Metronidazole 500 mg PO BID x7 days

Question 9

Treponemia pallidum early infection treatment of choice

Answer 9

Penicllin G benzathine 2.4 million units IM x1

Question 10

Treponema pallidum late infection treatment of choice

Answer 10

Penicillin G benzathine 2.4 million units IM weekly x3 doses

Question 11

Treponema pallidum neurosyphilis treatment of choice

Answer 11

Penicillin G 4 million units IV Q4H x10-14 days

Question 12

Gardnerella vaginalis treatment of choice

Answer 12

Metronidazole 500 mg PO BID x7 days

Question 13

A 27 year old pregnant woman is diagnosed with chlamydia during prenatal screening. The drug of choice for treatment of chlamydia during pregnancy is:

A) Levofloxacin
B) Ciprofloxacin
C) Azithromycin
D) Doxycycline

Answer 13

C - a single 1000 mg oral dose of azithromycin is preferred. A seven day course of amoxicillin or erythromycin base is an alternate regimen

Question 14

You are considering treatment options for a 32 year old woman with trichomoniasis. Which of the following is true regarding the use of metronidazole or tinidazole for this indication?

A) Metronidazole is less likely to cause GI ACEs
B) Intravaginal metronidazole is more effective than oral tinidazole
C) Tinidazole may be active against metronidazole-resistant strains
D) Clindamycin 2% cream topically at bedtime

Answer 14

C - Tinidazole is often effective against metronidazole-resistant T vaginalis, and is less likely to cause GI adverse effects than metronidazole, but tinidazole is considerably more expensive

Intravaginal metronidazole is not recommended for treatment of trichamoniasis

Question 15

Your patient today is a 19 yo woman. How many doses of Gardasil 9 (Human Papillomavirus Quadrivalent Vaccine) are recommended for a previously unvaccinated woman?

A) 2
B) 3
C) 4
D) None, your patient is too old for vaccination

Answer 15

C - Gardasil 9 is indicated for use in patients as old as 26 years. Two doses of the vaccine are recommended for boys and girls receiving the vaccine at 9-14 years old. A three dose series is still recommended when starting at 15-26 years, and also for immunocompromised patients