OA/RA Quiz

Question 1

Which statement is NOT correct?

A) Hepatic toxicity is the most serious side effect seen with acetaminophen
B) Hepatic toxicity is seen only after the daily dose of acetaminophen exceeds 12 grams
C) There is no evidence that one NSAID has better efficacy than another NSAID
D) Tramadol is a weak opioid mu agonist and also a weak inhibitor of serotonin and norepinephrine

Answer 1

B

Question 2

Which statement about DMARDs is correct?

A) Hydroxychloroquine, or methotrexate are two common non-biologic therapies used when a DMARD is indicated
B) When used as a DMARD the dose of methotrexate is the same as the dose used for the treatment of acute lymphocytic leukemia (ALL)
C) The dose of methotrexate in RA is 7.5 mg once daily for 4-6 weeks
D) TNF-alpha inhibitors are non biologic DMARDs

Answer 2

A - mtx as a DMARD is a much lower dose than treating ALL. TNF alpha inhibitors are biologics

Question 3

TNF-alpha inhibitors used in RA include: etanercept; infliximab; adalimumab; and golimumab. Which TNF-alpha inhibitor is a fusion protein rather than a monoclonal antibody?

A) Golimumab
B) Adalimumab
C) Infliximab
D) Etanercept

Answer 3

D

Question 4

Which statement is correct hydroxychloroquine?

A) The most common side effect of hydroxychloroquine is malaria
B) Hydroxychloroquine is used in combination with methotrexate in order to achieve a DMARD effect
C) When hydroxychloroquine is used to manage RA the expected response is seen in 2-4 weeks
D) Baseline otic and follow-up otic exams are recommended during treatment with hydroxychloroquine to detect deposits on the external ear canal

Answer 4

B

Question 5

Which statement about TNF-alpha inhibitors etanercept, adalimumab, and infliximab is correct?

A) All three can be given alone or in combination with methotrexate
B) Of these 3 agents - infliximab is NOT indicated for monotherapy
C) Enbrel TM is not indicated for monotherapy
D) Humira TN is not indicated for monotherapy

Answer 5

B