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Systems 3 - Endo-Repro > STI > Flashcards

STI Flashcards

1
Q

condoms most effective against…

A

chlamydia, gonorrhoea, ulcer disease, HPV (genital secretions)

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2
Q

chlamydia bacteria

A

C. tracheomatis

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3
Q

chlamydia infects…

A

mucosal epithelium eg oral, anal, cervical, vaginal

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4
Q

symptoms of chlamydia (5)

A 
urethral/vaginal discharge
rectal bleeding/discharge
dysuria
women: post coital bleeding
men: urethral itch

more than 50 per cent asymptomatic, more commonly women, rectal and throat

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5
Q

treatment of chlamydia

A

doxycycline/azithromycin

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6
Q

investigation for chlamydia

A

first catch urine NAAT/ vaginal or endocervical swab NAAT

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7
Q

natural history of chlamydia (women)

A

PID –> salpingitis –> ectopic/infertility

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8
Q

natural history of chlamydia (men)

A

complications of prostatitis/ epididymitis

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9
Q

gonorrhoea bacteria

A

N. gonorrhoea

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10
Q

gonorrhoea more common in…

A

MSM

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11
Q

gonorrhoea investigation

A

first catch urine/swab NAAT

resistance culture

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12
Q

gonorrhoea treatment

A

ceftriaxone and azithromycin (dual therapy, dec resistance)

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13
Q

gonorrhoea complication

A

disseminated gonococcal infection (female>male) –> longer treatment

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14
Q

genital warts cause

A

HPV (type 6 and 11 – non oncogenic)

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15
Q

genital warts spread

A

skin to skin - hands, feet and genitals

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16
Q

genital warts incubation

A

2wks - 8 yrs

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17
Q

genital warts treatment

A

cryotherapy
topical creams
often self limiting

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18
Q

HPV neoplastic types (intraepithelial neoplasia)

A

16 and 18

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19
Q

HPV vaccination

A

cervarix, gardasil, quadrivalent

20
Q

molluscum contagiosum

A

not warts, caused by pox virus

treated like warts

21
Q

common STI occurence (5) - high risk networks

A 
young
MSM
black afro carribean
inner cities
middle youth
22
Q

HIV prevalence in…

A

sub saharan Africa

23
Q

r0 (basic reproductive rate) =

A

BCD

B=probability of transmission
C= rate of partner acquisition
D= duration of infectiousness

24
Q

for STI increase R0 must be…

A

> 1

25
Q

for STI maintenance R0 must be…

A

=1

26
Q

for deadend network, R0 must be…

A

<1

27
Q

percentage unaware of HIV status in UK

A

around 30%

28
Q

highest risk HIV transmission

A

receptive anal intercourse, then insertive anal intercourse

29
Q

syphilis risk groups(3)

A

sex workers, MSM, subsaharan africa

30
Q

syphilis bacterium

A

spirachaete - Treponema pallidum

31
Q

syphilis transmission

A

vaginal, anal, oral sex

32
Q

syphilis incubation

A

9-90days (mean = 21)

33
Q

syphilis complications

A

neurosyphilis - stroke
CVS
gummatous

34
Q

syphilis presentation

A

chancre

secondary = polymorphic rash, systemic illness, mucous patches, condyloma lata

35
Q

syphilis investigation

A

blood test and wound exudate microscopy

36
Q

genital herpes cause

A

HSV 1/2

37
Q

genital herpes spread

A

genital, eye, oral (coldsores), anal

38
Q

genital herpes incubation

A

2days –> several weeks

39
Q

genital herpes symptoms

A

tingling
flu like prodrome
small vesicles –> ulcers
dysuria

latent infection in spinal nerve root ganglia

40
Q

genital herpes diagnosis

A

swab NAAT

41
Q

genital herpes treatment

A

aciclovir - 5-10days
analgesia
salt water
lignocaine

hosp if severe/ urinary retention
often mild and self limiting

42
Q

Hep B risk groups (6)

A

MSM
SE/E Asia
central africa
e. europe

injecting drug users
sex workers

43
Q

Hep B spread

A

vaginal/anal/oral sex, needlestick

vertical transmission

44
Q

Hep B virus type

A

DNA

45
Q

Hep B incubation

A

8-12 weeks

46
Q

Hep B complicaitons

A

liver failure/cirrhosis/carcinoma

Systems 3 - Endo-Repro (5 decks)

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