STI

Question 1

condoms most effective against…

Answer 1

chlamydia, gonorrhoea, ulcer disease, HPV (genital secretions)

Question 2

chlamydia bacteria

Answer 2

C. tracheomatis

Question 3

chlamydia infects…

Answer 3

mucosal epithelium eg oral, anal, cervical, vaginal

Question 4

symptoms of chlamydia (5)

Answer 4

urethral/vaginal discharge
rectal bleeding/discharge
dysuria
women: post coital bleeding
men: urethral itch

more than 50 per cent asymptomatic, more commonly women, rectal and throat

Question 5

treatment of chlamydia

Answer 5

doxycycline/azithromycin

Question 6

investigation for chlamydia

Answer 6

first catch urine NAAT/ vaginal or endocervical swab NAAT

Question 7

natural history of chlamydia (women)

Answer 7

PID –> salpingitis –> ectopic/infertility

Question 8

natural history of chlamydia (men)

Answer 8

complications of prostatitis/ epididymitis

Question 9

gonorrhoea bacteria

Answer 9

N. gonorrhoea

Question 10

gonorrhoea more common in…

Answer 10

MSM

Question 11

gonorrhoea investigation

Answer 11

first catch urine/swab NAAT

resistance culture

Question 12

gonorrhoea treatment

Answer 12

ceftriaxone and azithromycin (dual therapy, dec resistance)

Question 13

gonorrhoea complication

Answer 13

disseminated gonococcal infection (female>male) –> longer treatment

Question 14

genital warts cause

Answer 14

HPV (type 6 and 11 – non oncogenic)

Question 15

genital warts spread

Answer 15

skin to skin - hands, feet and genitals

Question 16

genital warts incubation

Answer 16

2wks - 8 yrs

Question 17

genital warts treatment

Answer 17

cryotherapy
topical creams
often self limiting

Question 18

HPV neoplastic types (intraepithelial neoplasia)

Answer 18

16 and 18

Question 19

HPV vaccination

Answer 19

cervarix, gardasil, quadrivalent

Question 20

molluscum contagiosum

Answer 20

not warts, caused by pox virus

treated like warts

Question 21

common STI occurence (5) - high risk networks

Answer 21

young
MSM
black afro carribean
inner cities
middle youth

Question 22

HIV prevalence in…

Answer 22

sub saharan Africa

Question 23

r0 (basic reproductive rate) =

Answer 23

BCD

B=probability of transmission
C= rate of partner acquisition
D= duration of infectiousness

Question 24

for STI increase R0 must be…

Answer 24

> 1

Question 25

for STI maintenance R0 must be...

Answer 25

=1

Question 26

for deadend network, R0 must be...

Answer 26

<1

Question 27

percentage unaware of HIV status in UK

Answer 27

around 30%

Question 28

highest risk HIV transmission

Answer 28

receptive anal intercourse, then insertive anal intercourse

Question 29

syphilis risk groups(3)

Answer 29

sex workers, MSM, subsaharan africa

Question 30

syphilis bacterium

Answer 30

spirachaete - Treponema pallidum

Question 31

syphilis transmission

Answer 31

vaginal, anal, oral sex

Question 32

syphilis incubation

Answer 32

9-90days (mean = 21)

Question 33

syphilis complications

Answer 33

neurosyphilis - stroke CVS gummatous

Question 34

syphilis presentation

Answer 34

chancre | secondary = polymorphic rash, systemic illness, mucous patches, condyloma lata

Question 35

syphilis investigation

Answer 35

blood test and wound exudate microscopy

Question 36

genital herpes cause

Answer 36

HSV 1/2

Question 37

genital herpes spread

Answer 37

genital, eye, oral (coldsores), anal

Question 38

genital herpes incubation

Answer 38

2days --> several weeks

Question 39

genital herpes symptoms

Answer 39

tingling flu like prodrome small vesicles --> ulcers dysuria latent infection in spinal nerve root ganglia

Question 40

genital herpes diagnosis

Answer 40

swab NAAT

Question 41

genital herpes treatment

Answer 41

aciclovir - 5-10days analgesia salt water lignocaine hosp if severe/ urinary retention often mild and self limiting

Question 42

Hep B risk groups (6)

Answer 42

MSM SE/E Asia central africa e. europe injecting drug users sex workers

Question 43

Hep B spread

Answer 43

vaginal/anal/oral sex, needlestick vertical transmission

Question 44

Hep B virus type

Answer 44

DNA

Question 45

Hep B incubation

Answer 45

8-12 weeks

Question 46

Hep B complicaitons

Answer 46

liver failure/cirrhosis/carcinoma