STI Flashcards
condoms most effective against…
chlamydia, gonorrhoea, ulcer disease, HPV (genital secretions)
chlamydia bacteria
C. tracheomatis
chlamydia infects…
mucosal epithelium eg oral, anal, cervical, vaginal
symptoms of chlamydia (5)
urethral/vaginal discharge rectal bleeding/discharge dysuria women: post coital bleeding men: urethral itch
more than 50 per cent asymptomatic, more commonly women, rectal and throat
treatment of chlamydia
doxycycline/azithromycin
investigation for chlamydia
first catch urine NAAT/ vaginal or endocervical swab NAAT
natural history of chlamydia (women)
PID –> salpingitis –> ectopic/infertility
natural history of chlamydia (men)
complications of prostatitis/ epididymitis
gonorrhoea bacteria
N. gonorrhoea
gonorrhoea more common in…
MSM
gonorrhoea investigation
first catch urine/swab NAAT
resistance culture
gonorrhoea treatment
ceftriaxone and azithromycin (dual therapy, dec resistance)
gonorrhoea complication
disseminated gonococcal infection (female>male) –> longer treatment
genital warts cause
HPV (type 6 and 11 – non oncogenic)
genital warts spread
skin to skin - hands, feet and genitals
genital warts incubation
2wks - 8 yrs
genital warts treatment
cryotherapy
topical creams
often self limiting
HPV neoplastic types (intraepithelial neoplasia)
16 and 18
HPV vaccination
cervarix, gardasil, quadrivalent
molluscum contagiosum
not warts, caused by pox virus
treated like warts
common STI occurence (5) - high risk networks
young MSM black afro carribean inner cities middle youth
HIV prevalence in…
sub saharan Africa
r0 (basic reproductive rate) =
BCD
B=probability of transmission
C= rate of partner acquisition
D= duration of infectiousness
for STI increase R0 must be…
> 1
for STI maintenance R0 must be…
=1
for deadend network, R0 must be…
<1
percentage unaware of HIV status in UK
around 30%
highest risk HIV transmission
receptive anal intercourse, then insertive anal intercourse
syphilis risk groups(3)
sex workers, MSM, subsaharan africa
syphilis bacterium
spirachaete - Treponema pallidum
syphilis transmission
vaginal, anal, oral sex
syphilis incubation
9-90days (mean = 21)
syphilis complications
neurosyphilis - stroke
CVS
gummatous
syphilis presentation
chancre
secondary = polymorphic rash, systemic illness, mucous patches, condyloma lata
syphilis investigation
blood test and wound exudate microscopy
genital herpes cause
HSV 1/2
genital herpes spread
genital, eye, oral (coldsores), anal
genital herpes incubation
2days –> several weeks
genital herpes symptoms
tingling
flu like prodrome
small vesicles –> ulcers
dysuria
latent infection in spinal nerve root ganglia
genital herpes diagnosis
swab NAAT
genital herpes treatment
aciclovir - 5-10days
analgesia
salt water
lignocaine
hosp if severe/ urinary retention
often mild and self limiting
Hep B risk groups (6)
MSM
SE/E Asia
central africa
e. europe
injecting drug users
sex workers
Hep B spread
vaginal/anal/oral sex, needlestick
vertical transmission
Hep B virus type
DNA
Hep B incubation
8-12 weeks
Hep B complicaitons
liver failure/cirrhosis/carcinoma
