Stevens-Johnson syndrome and toxic epidermal necrolysis Flashcards
1
Q
NB that the diseases are a spectrum. which is more severe?
A
toxic epidermal necrolysis
2
Q
features
A
flu like symptoms, burning eyes 1-3 days initially mouth ulcers, blister and peeling skin later extremely painful mucous membrnae invovlmenet
3
Q
complications
A
dehydration, sepsis, pneumonia, multi organ failure
4
Q
cause
A
carbamazepine, allopurinol infection
5
Q
SJS vs ten
A
SJS if <10% skin involved TEN ?30% skin involved
6
Q
what type of hyeprsensitivity
A
type IV
7
Q
treatment
A
dermatological emergency - burn unit/ITU like burns (IV fluids, NG feeding) treat the trigger (i.e. treat the infection or stop the drug)
8
Q
summarise
A
