Pemphigus vulgaris Flashcards
1
Q
pathology
A
autoimmune
anitbodies agains desmoglein
2
Q
more common in who
A
Ashkenazi jewish
3
Q
features
A
mucosal ulceration (differentiates from bullous pemphigoid)
skin blistering
painful but not itching
may be months between mouth and skin symptoms
4
Q
what is seen on biopsy
A
acantholysis - loss of intercellular connections resulting in loss of cohesion between keratinocytes
5
Q
rx
A
steroids
immunosuppressants
