Steven Johnson Syndrome Flashcards

1
Q

What is the MCC of SJS?

A

Meds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What meds cause SJS?

A
  • Sulfonamides (TMP-SMX)*
  • Allopurinol
  • Anti-seizure meds: Phenytoin, carbamazepine, Lamotrigine
  • Antipsychotics
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How much body surface area is involved?

A

<10%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the treatment for SJS?

A

Stop the drug & admit to burn center

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is SJS?

A

Mucocutaneous reaction w/detachment of epidermis & skin necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the MC drug that causes SJS?

A

Sulfa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the sxs?

A

Prodrome: fever, URI

Target lesions—> flaccid bullae

Mucous MBs ; positive Nikolsky sign

  • starts on face & trunk
  • ocular & pulmonary involvement
How well did you know this?
1
Not at all
2
3
4
5
Perfectly