Steroid-Responsive Meningitis-Arteritis Flashcards
1
Q
What is SRMA?
A
Vasculitis/arteritis affecting the meningeal vessels throughout the entire length of the spinal cord and brainstem
2
Q
What breeds are predisposed to SRMA? (5)
A
Beagle Bernese mountain dog Boxers German shepherd dogs Nova Scotia Duck Tolling Retriever
3
Q
What are the clinical signs of SRMA? (5)
A
Neck pain Reluctance to walk Arched spine Resistant to manipulation Fever
4
Q
CSF analysis results in SRMA and the complicating factor?
A
Increased protein
Neutrophilic pleocytosis
Within 24 hours of prednisolone administration, CSF may be normal or show mononuclear cells
5
Q
What disease can occur concurrently with SRMA?
A
Immune mediated polyarthritis
6
Q
What is the treatment for SRMA?
A
Immunosuppressive 2mg/kg q12h tapering over 4-6 months.
Azathioprine can be used if no response after 2 weeks
7
Q
What are the consequences of delayed treatment?
A
Neurological deficits associated with spinal cord infarction or meningeal fibrosis
