Sterile Compounding Flashcards
what meds must be prepared in a sterile manner?
opthalmic
IVs
irrigations
ISO sets the standards for air quality:
determined by # of _____ per ______ of a specific particle size
of particles per volume
lower number = cleaner air……
The PEC (primary engineering control -aka hood) has to be at least ISO ____
5
The PEC has to be ISO 5;
Buffer area = space outside PEC - has to be ISO ____
7
The ante area can be ISO ___ or ____ depending on if the buffer area is ______ or ______
ISO 7 or 8;
if positive or negative pressure
ISO 8 - for + pressure
ISO 7 - for - pressure
For PEC cleaning: clean with sterile ______ and _______ wipes
isopropyl alcohol 70% and sterile line free wipes
First air comes directly from ______ in a laminar (____ direction, ______) air flow
directly from HEPA filter;
one direction, parallel air flow
In a _______ laminar airflow workbench – nothing should b/w HPEA filter and sterile object
In a _______ laminar airflow workbench – nothing should be above the sterile object
^ dont want to block first iar
in horizontal
in a vertical
biological safety cabinets are used for chemo and other hazardous drugs and have ______ pressure airflow
negative
Isolators = glove boxes that are ISO 5 inside can be used for: hazardous, non-hazardous, or both?
both but have to use CACI for hazardous; CAIs for non-hazardous
IVs cans be made in a SCA (segregated compounding area) if no resources for a full IV room — the SCA has unclassified air but the BUD (beyond use data is less than _____)
12 hours
IV solutions need to be isotonic — which is blood has an osmolarity of _______ and pH close to 7
285 mOsm/L
Non-_____ bags should be used if leaching or sorption is an issue
Non-PVC
Hood can be on all the time or at least be turned on _______ before use
30 minutes
Hazardous drugs can be: \_\_\_\_\_\_genic \_\_\_\_\_\_genic Have \_\_\_\_\_\_\_ toxicity cause \_\_\_\_\_ toxicity at low doses \_\_\_\_\_toxic
carcinogenic teratogenic reproductive toxicity organ toxicity genotoxic
