STEMI Flashcards
STEMI
ST- elevation Myocardial Infarction
What is Myocardial Infarction
Myocardial cell death due to prolonged ischemia
difference between nstemi and stemi
stemi- development of full thickness cardiac muscle damage resulting from an acute interruption of blood supply to a part of the heart
nstemi- partial thickness damage of heart muscle
pathophysiology
-Formation of an occlusive thrombus in a major coronary artery previously affected by atherosclerosis.
-Cholesterol deposition within the wall of the artery is the main mechanism of atherosclerosis.
-This deposited cholesterol ultimately forms a plaque in the wall of the artery called atherosclerotic plaque.
-Sometimes this plaquemay rupture or erode, and can trigger platelet aggregation and fibrin deposition, which lead to formation of an occlusive thrombus in a coronary artery.
-This occlusive thrombus completely blocks a coronary artery and interrupts blood supply to part of the myocardium
-Profound changes take place in the myocardium that lead to irreversible changes and death of myocardial cells and ultimately ST-segment elevation myocardial infarction develops.