STEMI Flashcards

1
Q

STEMI

A

ST- elevation Myocardial Infarction

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2
Q

What is Myocardial Infarction

A

Myocardial cell death due to prolonged ischemia

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3
Q

difference between nstemi and stemi

A

stemi- development of full thickness cardiac muscle damage resulting from an acute interruption of blood supply to a part of the heart

nstemi- partial thickness damage of heart muscle

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4
Q

pathophysiology

A

-Formation of an occlusive thrombus in a major coronary artery previously affected by atherosclerosis.
-Cholesterol deposition within the wall of the artery is the main mechanism of atherosclerosis.
-This deposited cholesterol ultimately forms a plaque in the wall of the artery called atherosclerotic plaque.
-Sometimes this plaquemay rupture or erode, and can trigger platelet aggregation and fibrin deposition, which lead to formation of an occlusive thrombus in a coronary artery.
-This occlusive thrombus completely blocks a coronary artery and interrupts blood supply to part of the myocardium
-Profound changes take place in the myocardium that lead to irreversible changes and death of myocardial cells and ultimately ST-segment elevation myocardial infarction develops.

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