Stem Cells - UNIT 1 Flashcards
Difference between Embryonic Stem Cells and Tissue Stem Cells?
- EMBRYONIC cells are PLURIPORTANT so make ALL OF DIFFERENTIATED CELL TYPES of the body
- TISSUE cells are MULTIPOTANT so can differentiate into a limited number of cell types)
Epithelium tissue
Cover body surface and line body cavities
Connective Tissue
includes blood, bone and cartilage
Muscle Tissue
- form muscle tissue
- muscle cells can contract
Nervous Tissue
- form nerve cells
- main component of the nervous system
Why is cell division necessary in Somatic cells?
to allow organisms to grow, or to replace damaged cells and repair tissues
What is a germline cell?
diploid cells that can divide by mitosis or by meiosis to produce haploid gametes
Summarise meiosis
- Just before meiosis the DNA replicates itself
- a double division takes place so the nucleus is divided into 4 nuclei
- 4 new daughter cells are produced
- Each set of daughter chromosomes receives only one set of chromosomes
- At the end 4 haploid gametes are found
Difference between Germline and Somatic cells?
- If mutation occurs in a germline cell, the mutation is PASSED onto the offspring
- If mutation occurs in a somatic cell, ITS NOT PASSED onto the offspring however it may lead to a localised change of phenotype
2 areas stem cells are used to investigate
- how diseases develop
- drug testing
Therapeutic value of stem cells
- Bone Marrow Transplant
- Skin Grafts
- Corneal Transplant
How can cancer cells divide uncontrollably?
-cancer cells don’t respond to the usual regulatory signals and chemical messengers inside and outside the cell
Examples of agents that can cause genetic damage leading to cancer?
- smoking
- drinking
- eating too much