Stem Cells Flashcards
What are stem cells
Undifferentiated cells that are able to divide by mitosis & express all its genes
Types of potency
Totipotent
Pluripotent
Multipotent
Totipotent vs pluripotent vs multipotent
Uses of stem cells
Growth
Tissue repair
Cell replacement
Why do cells need to be differentiated & specialised
Multicellular organisms have small SA:V ratio’s so most cells aren’t in contact with the environment & so need to be specialised for particular functions
Sources of stem cells
Bone marrow
Embryo
Umbilical cord
Meristem (cambium)
Stem cells in the bone marrow can differentiate to
Erythrocytes
Neutrophils
Stem cells in the cambium can differentiate to
Xylem
Phloem
Ethical / issues of stem cells
Deny embryos right to life
Stem cell culture difficult & expensive
Even with immune suppressants, may be rejected by bodies
Uses of stem cells
Whole organ repair in organ transplants
Research into development biology
In Alzheimers & Parkinson’s disease to replace damaged cells
Damage tissue repair, in pancreas cells to treat diabetes nervous tissue to treat spinal/injuries