stem cells Flashcards
stem cells
embryonic stem cells are pleuripotent, adult stem cells have plasticity
stem cell niche
term used to describe the microenvironment of stem cells. Interacts with stem cells to regulate stem cell fate
adult stem cell splasticity
traditionally adult stem cells thought to have limited potential, only renewing tissue from which they are derived. Recent evidence suggests one tissue may transdifferentiate to renew other tissue types
reprogramming
adult skin cells have been genetically modded into induced pluripotent stem (iPS) cells. Theraputic potential is large, les ethical concerns, avoids immune rejection (come from individual
initiation and maintenance of cancer
emerging data from virtually all cancers suggests cancer may be maintained by a small amount of cancer stem cells resistant to traditional cancer therapies. When you kill off the cancer (radiation or chemotherapy), some resilient cancer stem cells can bring tumor back.