stem cell Flashcards
stem cell
undifferentiated cells that are ablet to differentiate into specialized cell types
what is a stem cell
a stem cell will differentiate into a self-renewal for copying and a specialized cell
two types of stem cells
- embryonic
-adult
(characterized by their potency)
embryonic stem cells (where to find them)
they are found in the inner cell mass of blastocyst. They can then be cultured in a lab to grow more cells.
Embryonic stem cells (what they can do)
embryonic stem cells can make all the different types of cell in the body. they are pluripotent.
potency
stem cells are characterized by their potential to differentiate into other types of cells. this is called potency. It decreases during this.
Types of stem cells (potency)
totipotent
pluripotent
multipotent
unipotent
Totipotent
able to differentiate into all possible cell types including the placenta. The zygote up to the 16 cell morula stage consists of totipotent
Pluripotent
able to differentiate into any of the germ layers. cells from the inner cell mass of the blastocysts are pluripotent
Multipotent
able to differentiate into a closely related family of cells. For example hematopoietic stem cells from the bone marrow can become red and white blood cells or platelets
Unipotent
able to only produce cells of their own type, but have the property of self-renewal required to be labeled a stem cell. Example include (adult) muscle stem cells.
Germ layers
Ectoderm
mesoderm
endoderm
ectoderm
neuron, skin cells and pigment cells
Mesoderm
skeletal muscle, smooth muscle, cardiac muscle, red blood cells and bone cells
endoderm
stomach cells, pancreatic cells, liver cells.