Eukaryotic cell cycle Flashcards
main phases
interphase- longest phases, the cell doubles its mass and duplicated its components mitosis- the nucleus divides cytokinesis- the cytoplasm divides
Interphase
-first phases, begins after the end of cell division
-made up of three phases G1, S and G2. G0 can also be a part of it after G1
G1
- first growth phase
-after cell division the cell is small so it grows back to its original size
-more organelles are produced
G0
cells will no longer divide but continue to perform their normal functions.
e.g. neurons, nerve or hear muscle cells
S
-synthesis phase
- cell duplicated its DNA (linear) to make two sister chromatids
G2
-second growth phase
-cell continues to grow and undergo metabolic activity
- the cell prepares cell division
- all the DNA is proofread to ensure no mistakes during Synthesis.
Checkpoints
G1- verifies that the cell has grown properly, has enough resources to continue and DNA has not been damaged
G2- ensures that DNA has replicated properly and the cell has enough resources more mitosis
Metaphase: In mitosis and checks formation of the spindle fibers. incorrect formation can lead to chromosome malfunctions.
Mitosis sub phases
Prophase, metaphase, Anaphase, Telophase
Prophase
- chromosome condenses and becomes visible
-centrosomes move towards the opposite sides of the cells (the poles)
-spindle fibers begin to form
-nuclear membrane disappears
Metaphase
-spindle fibers attach to chromones at centromeres
-chromones align at the equator between the poles
Anaphase
-the spindle fibers contract until the centromeres split, separating the sister chromatids
-the separated chromatids, now separate chromosomes are pulled towards the opposite poles by the spindle fibers.
Telophase
-nuclear membranes reform around the two sets of chromosomes
-the spindle fibres disappear
-the chromosomes decondense to become long thin chromatin fibres again.
Cytokinesis
can sometimes overlap with telophase
division of the cytoplasm
Cytokinesis in animal cells
-cytoplasm pinches in as a ring of contractile proteins squeezes the centre of the cell. called cleavage furrow
-two daughter cells are pinched apart
cytokinesis in plant cells
- a new plasma membrane and cell wall forms between the two cells
-this growth, called the cell plate begins int eh center of the cell, and grows until it fully separates the two daughter cells.