STD (lec 1) Flashcards
Vulvovaginal Candidiasis (VVC) is?
yeast infec (Not STD) (U) c. albacans
VVC presentation?
itching, burning
dyspareunia (painful sex)
thick, white d/c
VVC diagnostics?
Wet prep = buds/hyphae
Cx = candida
VVC tx?
Uncomplicated:
1-3 d topical azole
Complicated (≥4/yr, non-albican, DM, immuncomp):
7-14 d topical or
oral fluconazole
**if non-albicans, NO fluconazole (choose other azole)
VVC tx men?
Recurrent/difficult?
Preggos?
Not neces u/l blanitis
eval for DM, HIV
topical only
Bacterial Vaginosis (BV) is?
disruption in N flora, Not STD
(U) gard. vaginalis/mobiluncus G-var anaerobes
BV presentation?
Risks?
fishy, gray d/c
(P) ↑ risk HIV, HSV, gonor, chlam
BV diagnostics?
Amsel's (3 of 4): thin/white d/c clue cells vag pH >4.5 fishy KOH
Gram Stain = anaerobes and ↓ lactobacilli
BV tx?
Tx all symptomatic pts:
DOC: Oral Metro 7d (avoid etoh)
or Topical Metro 5d
or Clindamycin
**Preggos use ORAL!
No partner tx
Trichomoniasis caused by?
Presentation?
t. vaginalis
vag pH > 4.5
irrit, odor, yellow-green froth
petechiae cervix/vagina
Trichomoniasis diagnostics?
In men?
Wet mount = motile protoz
Nuc Acid Amp test (NAAT), esp for male
Difficult
5-20% of non-gon urethritis is trich
Trichomoniasis tx?
Treat pt and partners:
Oral Metro
No sex until well
Preggos -> tx if sxs
Trichomoniasis complications?
↑ risk HIV
Preggos -> preterms (tx doesn’t reduce risk)
No breast feeding during tx
Chlamydia (CT) screening?
yearly for under 26 yo or high risk
all preggos
frequent co-inf w/ gonorr
CT presentation?
(C) asympt
oral or rectal also P
Women:
CERVIX d/c, bleeding, low abd pain, fever/chills
Men:
urethritis, d/c, dysuria
CT diagnostics?
NAAT: Swab Urine Pap Pharynx/rectal
CT tx?
Treat all pts/partners:
Doxy 7d or Azith 1d
No sex for at least 7d
Retest 3-4 mo
Preggos:
NO doxy
Retest 3 wks post tx
CT complications?
↑ risk HIV
PID
Epididy
Preterms
Neonate eye inf/PNA
Gonorrhea (GC) screening?
at risk (prior inf, > partners, sex workers) (C) co-inf w/ CT
GC sxs?
Diag?
like CT, more severe
like CT
GC tx?
Treat all pts/partners:
ceftriaxone IM + azith or doxy
No sex
Retest 3-4 mo
GC complications?
same as CT
Neonate also meningitis, endocard
Non-gono Urethritis (NGU) caused by?
anything other than gonorr
(U) chlamy
NGU diagnostics?
Tx?
test for GC/CT
azith or doxy
PID is?
inflamm disorders of up genital tract
(U) from STDs (ascending infection)
(P) h. flu
PID presentation?
Acute:
d/c, low abd pain, cervical motion tenderness, fever
Chronic:
from insuff tx
vague sxs
PID risk factors?
< 25 yo blacks x partners IUD prior PID
PID diagnostics?
Serum quant HCG (pregnancy)
GC/CT
WBCs in vag fluid
CBC, ESR, CRP
US -> r/o ectopic, abscess
PID tx?
F/U?
Emphiric while waiting for tests
Outpt:
Ceftri IM +
Doxy 14d +
Metro 14d
Inpt:
IV
48 hr f/u
PID hospitalize when? (5)
can't r/o ectopic, append, etc preggos no abx response 48 hrs tubo-ovarian cysts looks ill
Fitz-Hugh-Curtis is?
(P) complication of PID
perihepatitis w/ RUQ pain/adhesions
HSV diagnostics?
Swab cx (standard): P false +, requires lesion
Ab serology:
Ab not present until 3 wks post
+ result not definitive for genital herp
HSV tx?
clovirs
Initial outbreak 7-10d
Recurrent 1-5d
Suppression daily
Neonatal HSV syndromes? (3)
1) Skin/Eye/Mouth (localized)
2) CNS (long-term morbidity)
3) Disseminated (organ involv)
Neonate HSV prevention?
Supression @ 36 wks for active/recurrent
C-section for active or prodrome
HPV diagnostics?
Visible warts
Pap smear
No test for men
HPV tx?
treat dzs caused by HPV, no cure
Destruction:
LN2, TCA
Podofilox
Imiquimod
Vaccine:
Cervarix (girls)
Gardasil (girls/boys)
HPV complications?
CA, esp cervical (U) types 16/18
rare transmission to neonate
Syphillis caused by?
At risk?
trep. pallidum
direct contact w/ lesion
(U) M 20-29yo
°Syphilis presents?
painless chancre 4-6 wks
2° Syphilis presents?
U 2-6 wks
No itch rash (U) includes palms/soles
Condyloma lata (moist warts) (U) intertriginous areas CONTAGIOUS
Mucous patches, not painful
mouth/genitals
CONTAGIOUS
Malaise, LAD
Latent Syphilis?
asympt
not transmittable
can last yrs
Late Syphilis?
yrs post infection
Neurosyphilis
Syphilis diagnostics?
Darkfield for chancre
Rapid Plasma Reagin -> titer = dz (confirm w/ FTA-ABS Ab test)
Neurosyphilis:
Lumbar punct -> VDRL test
Syphilis tx?
Treat all pts/partners:
Benazthine PCN-G IM single dose unless had dz for > 1 yr, then multi dose
Oral Doxy for PCN allergy
Confirm clearance w/ RPR titer 3, 6, 12, 24 mo
(4 x DECREASE = cleared)
Syphilis in preggos:
Complications? (4)
Screen?
stillbirths
deafness
neuro defects
bone deformities
screen at 1st visit
high risk again 28 wks and delivery
Close serology monitoring
Chancroid caused by?
Presentation?
h. ducreyi
Painful genital ulcer
Foul, contagious d/c
Inguinal adenitis/Buboes
Chancroid diagnostics?
r/o syphilis
report to county health
Lymphogranuloma Venereum (LGV) caused by?
Most at risk?
chlamydia trachomatis
MSM
LGV presentation? (5)
Systemic infection, Unilateral inguinal bubo (swollen node), Self-limit ulcer/papule Anal d/c or bleeding, Groove sign
LGV diagnostics?
r/o syphilis
report
Pediculosis Pubis tx?
Treat pt/partner:
permethrin 1% crm
STD screening for Pregnancy?
1st visit:
HIV, syphilis, Hep B, GC/CT
Hep C if risk
Hx for HSV