Starvation

Question 1

Basis

Answer 1

When there’s not enough food, body starts breaking down other things for energy
First breaks down spare molecules such as excess fats, spare proteins etc
Then shifts to more essential molecules such as muscle proteins and protective fat

Question 2

Tissue Metabolism

Answer 2

RBCs - only glucose
Brains - prefers glucose but ketones when necessary
Liver - always enough energy for itself and works to feed others

Question 3

Fed state

Answer 3

Liver will make and transport fat and make glycogen
adipose collects fat
Skl muscle makes glycogen
Heart uses beta ox fat
Brain uses glycolysis
RBCs use glycolysis

Question 4

Fasting State

Answer 4

Liver - use beta ox, breaks down glycogen
Adipose - lipolysis
Skl M - beta ox and ketogenesis
Heart - beta ox
brain - glycolysis
RBC - glycolysis

Question 5

Starving state

Answer 5

Liver - glycogenlysis, ketogenesis and beta ox, gluconeogen
Adipose - lipolysis
Skl M - ketogenesis, proteolysis
Heart - ketones
Brain -  ketones

Question 6

From Full to starve

Answer 6

1. use glucose just eaten
2. switch to liver glycogenolysis
3. Swith to liver gluconeogenesis
4. Alternate fuels

Question 7

Kwashrorkor

Answer 7

Normal caloric intake but not enough proteins therefore not essential AAs (his, Ile, Leu, Lys, Met, Phe, Thr, Try, Val)
No protein leads to hypoalbuminemia and edema
Liver becomes fatty and enlarged
Secondary infections occur due to complement def

Question 8

Marasmus

Answer 8

Not enough caloric intake, full body atrophy, Immune response still active