Staph aureus bacteraemia

Question 1

• Spectrum of S. aureus infections and source of bacteraemia
• Investigations of S.aureus bacteraemia
• Management of S. aureus Bacteraemia

Answer 1

.

Question 2

Staphylococci are gram …

Answer 2

positive

Question 3

List infections caused by staph aureus

Answer 3

Skin + soft tissue infections
Localised pyogenic staph infections, e.g. furuncles
Deep seated abscesses
Bone infection, e.g. OM
IE
Pneumonia

Question 4

Frequent sites of distant septic metastases

Answer 4

Bones + joints
IV discs
Heart valves

Question 5

Those more at risk of staph aureus colonisation

Answer 5

Type I DM
HIV
Haemodialysis

Question 6

Investigations of staph aureus bacteraemia

Answer 6

Microscopy + culture of specimens
MULTIPLE blood cultures - before antibiotics
Biopsy for bone infection
Imaging - CXR, CT, MRI, USS, ECHO

Question 7

Principles of treatment for invasive staph aureus bacteraemia

Answer 7

Antibiotics
Find source
Any surgical intervention

Question 8

Antibiotic used fore uncomplicated staph aureus bacteraemia

Answer 8

2 weeks IB flucloxacillin*

*1st line for MSSA

Question 9

Flucloxacillin is 1st line for MSSA

MRSA infections are targeted with what antibiotic

Answer 9

vancomycin

Question 10

Important to do what with blood cultures

Answer 10

REPEAT at 48-72 hours after antibiotics