Stains Memoriser Flashcards
SCC
Cytokeratins AE1/AE3, 34BE12, MNF116, 5/6, EMA, Ki-67
Paget’s disease of the breast
CAM 5.2, CK7, CEA
Non-gastric adenocarcinoma
CK7
Merkel cell carcinoma
CK20 (perinuclear dot); Synaptophysin, Chromogranin, Neuron-specific enolase
TTF-1 NEGATIVE
Metastatic adenocarcinoma
CDX2, CK7, CK20 (CK7/20 can be useful to identify location, among other stains)
Sebaceous carcinoma
EMA, adipophilin
Epithelioid sarcoma
EMA
Adnexal neoplasms
CEA
BCC
BerEp4 (negative EMA)
Metastatic renal cell carcinoma
RCC
Metastatic small-cell lung carcinoma
TTF-1 (as compared with MCC, which is positive)
Desmoplastic melanoma
S100, Sox10
Spitz naevi
S100A6
Cellular neurothekeoma
S100A6, MITF
Langerhans cell histiocytosis
S100, CD1a
Rosai-dorfman disease
S100
Granular cell tumour
S100
Neurofibroma
S100
AFX
S100A6
Naevi
Melan-A/MART-1