Stains Memoriser Flashcards
SCC
Cytokeratins AE1/AE3, 34BE12, MNF116, 5/6, EMA, Ki-67
Paget’s disease of the breast
CAM 5.2, CK7, CEA
Non-gastric adenocarcinoma
CK7
Merkel cell carcinoma
CK20 (perinuclear dot); Synaptophysin, Chromogranin, Neuron-specific enolase
TTF-1 NEGATIVE
Metastatic adenocarcinoma
CDX2, CK7, CK20 (CK7/20 can be useful to identify location, among other stains)
Sebaceous carcinoma
EMA, adipophilin
Epithelioid sarcoma
EMA
Adnexal neoplasms
CEA
BCC
BerEp4 (negative EMA)
Metastatic renal cell carcinoma
RCC
Metastatic small-cell lung carcinoma
TTF-1 (as compared with MCC, which is positive)
Desmoplastic melanoma
S100, Sox10
Spitz naevi
S100A6
Cellular neurothekeoma
S100A6, MITF
Langerhans cell histiocytosis
S100, CD1a
Rosai-dorfman disease
S100
Granular cell tumour
S100
Neurofibroma
S100
AFX
S100A6
Naevi
Melan-A/MART-1
Melanoma
S100, Melan-A/MART-1, Sox10, MITF
Schwannoma
Sox10
Sarcoma
Vimentin
Piloleiomyoma
Desmin, SMA
Leiomyosarcoma
Desmin
Glomus tumour
SMA
Glomangioma
SMA
DFSP
CD34
Angiosarcoma
CD31
Infantile haemangioma
GLUT1
Perineurioma
GLUT1
Dermatofibroma
Factor XIIIa
Lymphangioma
D2-40
Lymphovascular invasion
D2-40
B-cell lymphomas
CD19, CD20, CD79a
T-cell lymphomas
CD3, CD4, CD8
Mycoses fungoides
CD3, CD4, CD8, CD5 and 7 loss, CD30 with transformation
CLL
CD5, CD23
Mantle cell lymphoma
CD5, (CD 23 negative), Bcl2
Anaplastic large-cell lymphoma
CD30
Lymphomatoid papulosis
CD30
Elastic plasmacytoid dendritic cell neoplasm
CD56
Histiocytic markers
CD68, and CD163
AML
Myeloperoxidase
Multiple myeloma
CD138
Urticaria pigmentosa
CD117 (c-Kit)
Follicle centre cell lymphoma
Bcl6, CD10
Diffuse large B-cell lymphoma, leg type
MUM-1
Syphilis
Spirochete stain
HSV
HSV stain
VZV
VZV stain
Kaposi’s sarcoma
HHV-8 stain