Commonly Used Immunohistochemical Stains Flashcards
P63
Epithelial marker
Cutaneous spindle cell squamous carcinoma
CAM5.2
Epithelial marker
Paget disease, extramammary Paget disease
CK7
Epithelial marker
Paget disease, extramammary Paget disease
CK20
Epithelial marker
Merkel cell carcinoma
EMA (Epithelial membrane antigen)
Epithelial marker
Squamous cell carcinoma
CEA (carcinoembryonic antigen)
Epithelial marker
Sweat gland neoplasms
Paget disease
EMPD
Desmin
Mesenchymal marker
Skeletal and smooth muscle tumours (leiomyoma)
Smooth muscle actin (SMA)
Mesenchymal marker
Glomus tumour
Leiomyosarcoma
CD34
Mesenchymal marker
Dermatofibrosarcoma protuberano, trichoepitheliomas
Factor XIIIa
Mesenchymal marker
Dermatofibroma
CD31
Mesenchymal marker
Vascular tumours
D2-40
Mesenchymal marker
Lymphatic endothelial marker
GLUT1
Mesenchymal marker
Infantile haemangioma
Vimentin
Mesenchymal marker
Sarcomas
S100
Neuroectodermal marker
Desmoplastic melanoma
Langerhans cell histiocytosis
Granular cell tumour
HMB-45
Neuroectodermal marker
Desmoplastic melanoma
Blue naevus
Melan-A, Mart-1
Neuroectodermal marker
Desmoplastic melanoma
CD45Ra (LCA)
Haematopoietic marker
Haematolymphoid proliferation
CD20
Haematopoietic marker
B-cell lymphomas
CD10
Haematopoietic marker
Atypical fibroxanthomas
Clear-cell hidradenoma
Sebaceous tumours
CD79a
Haematopoietic marker
Plasma cell, B cell marker
CD138
Haematopoietic marker
Plasma cell marker
CD3
Haematopoietic marker
T-cell lemphomas
CD4
Haematopoietic marker
T-helper lymphocytic marker
CD5
Haematopoietic marker
Mantle cell lymphoma
Chronic lymphocytic leukaemia
CD7
Haematopoietic marker
Often lost in T-cell lymphomas
CD8
Haematopoietic marker
T-cell cytotoxic/suppressor marker
CD30
Haematopoietic marker
Anaplastic large cell lymphoma
Lymphomatoid papulosis
Chronic arthropod bites
CD1a
Haematopoietic marker
Langerhans cell histiocytosis
Langerin (CD207)
Haematopoietic marker
Langerhans cell histiocytosis
BCL2
Haematopoietic marker
B-cell lymphoproliferative disorders
HHV-8
Infective marker
Kaposi sarcoma
Sox10
Neuroectodermal marker
Desmoplastic melanoma