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Derm Revision > Commonly Used Immunohistochemical Stains > Flashcards

Commonly Used Immunohistochemical Stains Flashcards

1
Q

P63

A

Epithelial marker

Cutaneous spindle cell squamous carcinoma

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2
Q

CAM5.2

A

Epithelial marker

Paget disease, extramammary Paget disease

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3
Q

CK7

A

Epithelial marker

Paget disease, extramammary Paget disease

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4
Q

CK20

A

Epithelial marker

Merkel cell carcinoma

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5
Q

EMA (Epithelial membrane antigen)

A

Epithelial marker

Squamous cell carcinoma

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6
Q

CEA (carcinoembryonic antigen)

A

Epithelial marker

Sweat gland neoplasms
Paget disease
EMPD

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7
Q

Desmin

A

Mesenchymal marker

Skeletal and smooth muscle tumours (leiomyoma)

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8
Q

Smooth muscle actin (SMA)

A

Mesenchymal marker

Glomus tumour
Leiomyosarcoma

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9
Q

CD34

A

Mesenchymal marker

Dermatofibrosarcoma protuberano, trichoepitheliomas

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10
Q

Factor XIIIa

A

Mesenchymal marker

Dermatofibroma

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11
Q

CD31

A

Mesenchymal marker

Vascular tumours

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12
Q

D2-40

A

Mesenchymal marker

Lymphatic endothelial marker

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13
Q

GLUT1

A

Mesenchymal marker

Infantile haemangioma

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14
Q

Vimentin

A

Mesenchymal marker

Sarcomas

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15
Q

S100

A

Neuroectodermal marker

Desmoplastic melanoma
Langerhans cell histiocytosis
Granular cell tumour

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16
Q

HMB-45

A

Neuroectodermal marker

Desmoplastic melanoma
Blue naevus

17
Q

Melan-A, Mart-1

A

Neuroectodermal marker

Desmoplastic melanoma

18
Q

CD45Ra (LCA)

A

Haematopoietic marker

Haematolymphoid proliferation

19
Q

CD20

A

Haematopoietic marker

B-cell lymphomas

20
Q

CD10

A

Haematopoietic marker

Atypical fibroxanthomas
Clear-cell hidradenoma
Sebaceous tumours

21
Q

CD79a

A

Haematopoietic marker

Plasma cell, B cell marker

22
Q

CD138

A

Haematopoietic marker

Plasma cell marker

23
Q

CD3

A

Haematopoietic marker

T-cell lemphomas

24
Q

CD4

A

Haematopoietic marker

T-helper lymphocytic marker

25
Q

CD5

A

Haematopoietic marker

Mantle cell lymphoma
Chronic lymphocytic leukaemia

26
Q

CD7

A

Haematopoietic marker

Often lost in T-cell lymphomas

27
Q

CD8

A

Haematopoietic marker

T-cell cytotoxic/suppressor marker

28
Q

CD30

A

Haematopoietic marker

Anaplastic large cell lymphoma
Lymphomatoid papulosis
Chronic arthropod bites

29
Q

CD1a

A

Haematopoietic marker

Langerhans cell histiocytosis

30
Q

Langerin (CD207)

A

Haematopoietic marker

Langerhans cell histiocytosis

31
Q

BCL2

A

Haematopoietic marker

B-cell lymphoproliferative disorders

32
Q

HHV-8

A

Infective marker

Kaposi sarcoma

33
Q

Sox10

A

Neuroectodermal marker

Desmoplastic melanoma

Derm Revision (5 decks)

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