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Derm Revision > Commonly Used Immunohistochemical Stains > Flashcards

Commonly Used Immunohistochemical Stains Flashcards

1
Q

P63

A

Epithelial marker

Cutaneous spindle cell squamous carcinoma

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2
Q

CAM5.2

A

Epithelial marker

Paget disease, extramammary Paget disease

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3
Q

CK7

A

Epithelial marker

Paget disease, extramammary Paget disease

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4
Q

CK20

A

Epithelial marker

Merkel cell carcinoma

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5
Q

EMA (Epithelial membrane antigen)

A

Epithelial marker

Squamous cell carcinoma

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6
Q

CEA (carcinoembryonic antigen)

A

Epithelial marker

Sweat gland neoplasms
Paget disease
EMPD

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7
Q

Desmin

A

Mesenchymal marker

Skeletal and smooth muscle tumours (leiomyoma)

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8
Q

Smooth muscle actin (SMA)

A

Mesenchymal marker

Glomus tumour
Leiomyosarcoma

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9
Q

CD34

A

Mesenchymal marker

Dermatofibrosarcoma protuberano, trichoepitheliomas

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10
Q

Factor XIIIa

A

Mesenchymal marker

Dermatofibroma

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11
Q

CD31

A

Mesenchymal marker

Vascular tumours

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12
Q

D2-40

A

Mesenchymal marker

Lymphatic endothelial marker

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13
Q

GLUT1

A

Mesenchymal marker

Infantile haemangioma

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14
Q

Vimentin

A

Mesenchymal marker

Sarcomas

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15
Q

S100

A

Neuroectodermal marker

Desmoplastic melanoma
Langerhans cell histiocytosis
Granular cell tumour

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16
Q

HMB-45

A

Neuroectodermal marker

Desmoplastic melanoma
Blue naevus

17
Q

Melan-A, Mart-1

A

Neuroectodermal marker

Desmoplastic melanoma

18
Q

CD45Ra (LCA)

A

Haematopoietic marker

Haematolymphoid proliferation

19
Q

CD20

A

Haematopoietic marker

B-cell lymphomas

20
Q

CD10

A

Haematopoietic marker

Atypical fibroxanthomas
Clear-cell hidradenoma
Sebaceous tumours

21
Q

CD79a

A

Haematopoietic marker

Plasma cell, B cell marker

22
Q

CD138

A

Haematopoietic marker

Plasma cell marker

23
Q

CD3

A

Haematopoietic marker

T-cell lemphomas

24
Q

CD4

A

Haematopoietic marker

T-helper lymphocytic marker

25
CD5
Haematopoietic marker Mantle cell lymphoma Chronic lymphocytic leukaemia
26
CD7
Haematopoietic marker Often lost in T-cell lymphomas
27
CD8
Haematopoietic marker T-cell cytotoxic/suppressor marker
28
CD30
Haematopoietic marker Anaplastic large cell lymphoma Lymphomatoid papulosis Chronic arthropod bites
29
CD1a
Haematopoietic marker Langerhans cell histiocytosis
30
Langerin (CD207)
Haematopoietic marker Langerhans cell histiocytosis
31
BCL2
Haematopoietic marker B-cell lymphoproliferative disorders
32
HHV-8
Infective marker Kaposi sarcoma
33
Sox10
Neuroectodermal marker Desmoplastic melanoma

Derm Revision (5 decks)

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