SSTI

Question 1

mild impetigo

Answer 1

• topical mupirocin

Question 2

impetigo, ecthyma (multiple lesions)

Answer 2

EMPIRIC
- PO cephalexin, cloxacillin
- penicillin allergy: clindamycin

CULTURE DIRECTED
- S.pyogenes: PO Penicillin, amoxicillin
- MSSA: cephalexin, cloxacillin

7 DAYS

Question 3

purulent SSTI

Answer 3

MILD
- I&D or warm compress

MODERATE with systemic
- I&D + oral Abx
** cloxacillin, cephalexin, clindamycin

SEVERE
- I&D + IV
** cloxacillin, cefazolin, clindamycin, vancomycin

MRSA
- cotrimoxazole, doxycycline, clindamycin
- vancomycin, daptomycin, linezolid

GRAM -VE ANAEROBE
- augmentin

5-10 DAYS

Question 4

nonpurulent SSTI

Answer 4

MILD
- penicillin, cephalexin, cloxacillin
- clindamycin

MODERATE (systemic)
- cover MSSA with IV
- cefazolin, cloxacillin, clindamycin

SEVERE
- IV: pip-tazo, cefepime, meropenem
- MRSA: vancomycin, daptomycin, linezolid

5-10 DAYS, 14 if immunocompromised