SSSI/Osteo Flashcards
PURULENT: Mild/Moderate
Furuncle, Carbuncle, Abscess
Mild: I/D
Mod: I/D
-Empiric: TMP/SMX or Doxy
-Defined:
*MRSA: TMP/SMX
*MSSA: Dicloxacillin or Cephalexin
PURULENT: Severe
Furuncle, Carbuncle, Abscess
Empiric:
-VANCO or
-DAPTO or
-LINEZOLID or
-TELEVANCIN or
-CEFTAROLINE
Defined:
-MRSA: same as empiric
-MSSA: NAF, CEFAZOLIN, CLINDA
NONPURULENT: Mild/Moderate
Necrotizing, Cellulitis, Erysipelas
Mild: ORAL
-Penicillin or
-Cephalosporin or
-Dicloxacillin or
-Clindamycin
Moderate: IV
-Penicillin
-Ceftriaxone
-Cefazolin
-Clindamycin
NONPURULENT: Severe
Necrotizing, Cellulitis, Erysipelas
Empiric:
-VANCO AND ZOSYN
Defined:
*if poly - same as empiric
*if mono - below
-Pyogenes/Clostridial: PEN AND CLINDA
-Vibrio: DOXY AND CEFTAZIDIME
-Aeromonas: DOXY AND CIPRO
Definition of Mod/Sev
Moderate
-SSTI with systemic signs/sx
Severe
-Purulent: Fever 38+, HR 90+, RR 24+, WBC 12+, IC
-Non: same ^ plus failed oral therapy or skin sloughing
Bite Wounds
-Amox/Clav
-Doxy
-Levo/moxifloxacin
MC LAD
Overview of Purulent MRSA/MSSA
Doxy, Clinda, Bactrim
Overview of Non-Purulent Strep
Cephalexin, Clinda
Mild Diabetic Foot Infections
Staph/Strep
-Clinda
-Cephalexin
-Levofloxacin
-Amox/Clav
-Doxy
-TMX/Sulf
oral agents: LAD needs TLC
Moderate DFI
Oral or IV
-Levo/moxifloxacin
-Clinda, cipro
-Ceftriaxone, Cefoxitin
-Amp/Sul
FATMCCL
Severe DFI
-Ertapenem, meropenem, imipenem
-Zosyn
-Ceftazidime, aztreonam
-Cefepime
-Vanco, dapto, line
VDL + PAD + MTZ or VDL + ZC
Osteomyelitis
-Should cover MRSA, Enterobacteriaceae, and +/- P. aeruginosa
Pseudomonas (PA) coverage: MIZ TAP
-Imipenem, Meropenem, Zosyn
-Ceftazidime, Aztreonam, Cefepime
Duration
-No residual infected tissue: 2-5 days
-Residual soft tissue infection: 1-3 weeks
-Residual viable infected bone: 4-6 weeks
-No surgery or residual dead bone: ≥ 3 months
