SSchz

Question 1

What did Gottesman do?

Answer 1

• large scale family study that showed schz in families and twins

Question 2

What were the findings of Gottesman’s study?

Answer 2

• it showed that if one identical twin had schz then the other twin is at a 48% chance of also having schz. comapred to non-identical twins where it was a 17% chance.

Question 3

Evaluate Gottesman’s study?

Answer 3

• it showed a positive correlation between genetic similarity and the risk of schz.
  -however, a limitation of this is that it is retrospective data.

Question 4

What is retrospective data?

Answer 4

• a retrospective study using existing data that have been recorded for reasons other than the research .

Question 5

What does it mean for schz to be polygenic?

Answer 5

• meaning several genes are involved in the development of schz.

Question 6

What does aetiologically heterogeneous?

Answer 6

• it means there are different combinations of genes.