Spondyloarthropathy Flashcards

1
Q

Types of spondyloarthropathies

A
  • Ankylosing spondylitis
  • Psoriatic arthritis
  • Reactive arthritis
  • Reiter’s syndrome
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2
Q

Common characteristics of spondyloarthropathies

A
  • AsEnIn

- RInHig

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3
Q

I made up AsEnIn to stand for

A
  • Asymmetrical peripheral arthritis
  • Enthesopathy
  • Inflammatory axial spine involvement
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4
Q

I made up RInHig to stand for

A
  • Rheumatoid factor negative
  • Inflammatory eye disease
  • High frequency of HLA B27
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5
Q

What is enthesopathy?

A

inflammation where a ligament or tendon attaches to bone

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6
Q

Arthritis associated with spondyloarthropathies is (asymmetrical, symmetrical)

A

asymmetrical

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7
Q

________ of those with __________________ are HLA-B27+

A

24%; spondyloarthropathies

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8
Q

________ of those with ___________ have AS.

A

1.8%; HLA-B27

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9
Q

AS stands for

A

Ankylosing Spondylitis

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10
Q

24% of those with spondyloarthropathies are

A

HLA-B27+

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11
Q

1.8% of those with HLA-B27 have

A

AS

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12
Q

HLA-B27 Disease Associations - AS

A

> 90%

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13
Q

HLA-B27 Disease Associations - Reiter’s syndrome

A

80%

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14
Q

HLA-B27 Disease Associations - Reactive arthritis

A

85%

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15
Q

HLA-B27 Disease Associations - IBD

A

50%

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16
Q

HLA-B27 Disease Associations - Psoriatic arthritis

A

65%

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17
Q

What disease has >90% association with HLA-B27?

A

AS

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18
Q

What disease has 80% association with HLA-B27?

A

Reiter’s syndrome

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19
Q

What disease has 85% association with HLA-B27?

A

Reactive arthritis

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20
Q

What disease has 50% association with HLA-B27?

A

IBD

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21
Q

What disease has 65% association with HLA-B27?

A

Psoriatic arthritis

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22
Q

IBD stands for

A

Inflammatory Bowel Disease

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23
Q

Ankylosing Spondylitis - general information

A
  • Onset < 40 yo
  • Insidious
  • > 3 months
  • Morning stiffness
  • < with exercise
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24
Q

What does insidious mean?

A

long, slow onset

25
Diagnosis of AS
- LiNoL | - BeRUnBi
26
I made up LiNoL to stand for
- Limited lumbar motion - Not relieved by rest (made worse) - LBP > 3 months
27
I made up BeRUnBi to stand for
- Better with exercise - Reduced chest expansion - Unilateral sacroiliitis on x-ray - Bilateral sacroiliitis on x-ray
28
Reduced chest expansion in a pt with AS can cause what?
difficulty breathing
29
Typically seen in a pt with AS when asked to bend over to touch toes:
- Flat lumbar spine - < lordosis - Use hips for bending
30
AS non-vertebral symptoms
- CoSAr - AsIrI - PlAc
31
I made up CoSAr to stand for
- Costochondritis - Sausage digits (not as common) - Arthritis of toe IP joints
32
I made up AsIrI to stand for
- Asymmetrical peripheral arthritis - Iritis - IBD
33
I made up PlAc to stand for
- Plantar fasciitis | - Achilles tenosynovitis
34
PT treatment of AS
- Exercise - Posture - Hot/cold (depending on pt)
35
What type of exercise in particular is good for pts with AS?
aerobic and ROM
36
Medications for AS
- Anti-inflammatory - Corticosteroids - Sulfasalazine - DMARDs - TNF blockers
37
Side effects of sulfasalazine
- Anorexia - Headache - Nausea - Vomiting - Gastric distress
38
Side effects of TNF blockers
- Convulsions - Multiple sclerosis - Transverse myelitis - Paresthesias - Infections - CHF
39
What medication commonly presents with the side effects of anorexia, headache, nausea, vomiting, and gastric distress?
Sulfasalazine
40
What medication commonly presents with the side effects of convulsions, multiple sclerosis, transverse myelitis, paresthesias, infections, and CHF?
TNF blockers
41
PT implications of spondyloarthropathies
- New onset of back pain - Teach posture - During flare ups
42
What are the PT implications of a pt with spondyloarthropathy who develops a new onset of back pain?
- Fever - Fatigue (think AS)
43
What are the PT implications of a pt with spondyloarthropathy in the middle of a flare up?
- Avoid aggressive stretching - Use modalities - Use gentle aerobic exercise
44
Reiter's syndrome aka
reactive arthritis
45
reactive arthritis aka
Reiter's syndrome
46
Reiter's syndrome (reactive arthritis) is a _______________________ arthritis.
seronegative; asymmetric
47
What does seronegative mean?
no rheumatoid factor
48
Reiter's syndrome (reactive arthritis) is a seronegative asymmetric arthritis following:
- Urethritis or cervicitis | - Infectious diarrhea
49
What diseases is Reiter's syndrome (reactive arthritis) associated with?
- Inflammatory eye disease - Enthesopathy - Sacroiliitis
50
What eye symptom is commonly seen in pts with Reiter's syndrome (reactive arthritis)?
conjunctivitis
51
What is conjunctivitis?
inflammation of the outer layer of the eye/inner layer of eyelid; aka pink eye
52
What foot symptom is commonly seen in pts with Reiter's syndrome (reactive arthritis)?
heel tendonitis
53
What low back symptom is commonly seen in pts with Reiter's syndrome (reactive arthritis)?
asymmetrical sacroiliitis
54
Medications for Reiter's syndrome (reactive arthritis)
- Anti-inflammatory - Corticosteroids - Antibiotics - DMARDs - TNF blockers
55
Psoriatic arthritis - prevalence
- 2% of people have psoriasis | - 5-7% of those with psoriasis develop Psoriatic arthritis
56
Psoriatic arthritis - symptoms
- Inflammatory arthritis of DIPs - Asymmetrical arthritis - Sausage digits (definitely) - Nail pitting - Enthesopathy
57
What type of arthritis is called "pencil in a cup"?
Psoriatic arthritis
58
Psoriatic arthritis - changes in phalangeal joints
severe in DIPs, less in PIPs, minimal in MTPs
59
Spondyloarthropathy associations
- Inflammatory bowel disease | - Inflammatory eye disease