Spondyloarthropathy Flashcards
Types of spondyloarthropathies
- Ankylosing spondylitis
- Psoriatic arthritis
- Reactive arthritis
- Reiter’s syndrome
Common characteristics of spondyloarthropathies
- AsEnIn
- RInHig
I made up AsEnIn to stand for
- Asymmetrical peripheral arthritis
- Enthesopathy
- Inflammatory axial spine involvement
I made up RInHig to stand for
- Rheumatoid factor negative
- Inflammatory eye disease
- High frequency of HLA B27
What is enthesopathy?
inflammation where a ligament or tendon attaches to bone
Arthritis associated with spondyloarthropathies is (asymmetrical, symmetrical)
asymmetrical
________ of those with __________________ are HLA-B27+
24%; spondyloarthropathies
________ of those with ___________ have AS.
1.8%; HLA-B27
AS stands for
Ankylosing Spondylitis
24% of those with spondyloarthropathies are
HLA-B27+
1.8% of those with HLA-B27 have
AS
HLA-B27 Disease Associations - AS
> 90%
HLA-B27 Disease Associations - Reiter’s syndrome
80%
HLA-B27 Disease Associations - Reactive arthritis
85%
HLA-B27 Disease Associations - IBD
50%
HLA-B27 Disease Associations - Psoriatic arthritis
65%
What disease has >90% association with HLA-B27?
AS
What disease has 80% association with HLA-B27?
Reiter’s syndrome
What disease has 85% association with HLA-B27?
Reactive arthritis
What disease has 50% association with HLA-B27?
IBD
What disease has 65% association with HLA-B27?
Psoriatic arthritis
IBD stands for
Inflammatory Bowel Disease
Ankylosing Spondylitis - general information
- Onset < 40 yo
- Insidious
- > 3 months
- Morning stiffness
- < with exercise