Sjogren's_Polymyalgia Rheumatica Flashcards
Common symptoms seen with Sjogren’s
- dry eyes with damage to eye surface
- dry mouth with increased tooth decay
Sjogren’s - general information
- women 30’s and 50’s
- systemic autoimmune disease
- characteristic ocular and salivary
- lung (pneumonitis)
- kidney (interstitial nephritis)
- neurological (central and peripheral)
Sjogren’s - causes
- Genetic
- Environment
Genetic factors associated with Sjogren’s
HLA-DR
Environment factors associated with Sjogren’s
- no single agent identified
- virus
What is xerostomia?
dry mouth
Sjogren’s - eye and oral features
- positive ANA
- specific needs for eye and mouth care
Sjogren’s pts need moisture because they are typically very
dry and thirsty
Additional symptoms associated with Sjogren’s
- submandibular salivary gland enlargement
- parotid gland enlargement
- salivary gland infection
- vasculitis
- fatigue
- cognitive loss
Why are salivary gland infections common in pts with Sjogren’s?
lack of production of saliva (dry mouth)
Extraglandular manifestations of Sjogren’s
- Lung: interstitial pneumonitis
- Renal: interstitial nephritis
- Cardiac: pulmonary HTN
- Hematologic: lymphoma
- Joint pain: arthritis
- Neurologic: peripheral neuropathy
Symptoms associated with interstitial pneumonitis
- congestion
- interstitial infiltrate
- intra-alveolar edema
Arthritis associated with Sjogren’s is (symmetrical, asymmetrical)
asymmetrical
Grades of peripheral neuropathy
- 1-4, with 4 being the worst
Medications for Sjogren’s
- Anti-inflammatory
- Corticosteroids
- Antimalarials
- DMARDs
