spondyloarthropathies overview .

Question 1

define spondyloarthropathy

Answer 1

family of inflammatory arthrides characterised by involvement of the spine and other joints

principally in genetically predisposed - HLA B27 +ve

Question 2

what is the gene that genetically predisposes you to spondyloarthropathy

Answer 2

HLA B27

Question 3

what are the diseases associated with HLA B27 subtype

Answer 3

PAIR

psoraitic arthritis
ankylosing spondylitis
IBS and enteropathic arthritis
reactive arthritis

Question 4

what are the shared rheumatological features of spondyloarthritis

Answer 4

SI joint and spine involvement

inflammatory arthritis

synovitis

enthesitis

dactylitis

Question 5

what are the features of an inflammatory arthritis

Answer 5

oligoarticuular

asymmetrical

predominantly lower limb

Question 6

what is synovitis

Answer 6

inflammation of joint and tendon sheath linings

Question 7

what is enthesitis

Answer 7

inflammation of the sites where tendons and ligaments attach to bones

e.g. achilles teninitis, plantar fascitis

Question 8

what is dectylitis

Answer 8

‘sausage digits’

inflammation of the entire digit

Question 9

what are the shared extra-articular features or spondyloarthropathy

Answer 9

occular inflammation

mucocutaneous lesions

no rheumatoid nodules

rare aortic incompetence or heart block