spondyloarthropathies Flashcards
what are spondyloarthropathies?
group of inflammatory rheumatic diseases that primarily affect the spine and peripheral joints
what are the different types of spondyloarthropathies?
-ankylosing spondylities
-Psoriatic Arthritis
-Reactive Arthritis:
-Enteropathic Arthritis
-Undifferentiated Spondyloarthropathy
how are spondyloarthropathies diagnosed?
-all rheumatological conditions are made with a clinical history supported by radiological investigations and blood tests
my patient has back pain - how do I know its inflammatory?
-pain that docent settle after rest
-responds well to NSAIDS
-family history
-age (less than 40 yrs)
-morning stiffness (more than 30 mins)
-pain at night which may wake pt during second half of the night
compare inflammatory back pain vs mechanical back pain
IBP
-age of onset (less than 40), -pain improves with exercise
- pain does not improve w/ rest
-morning stiffness (more than 30m)
MBP
-can happen at any age
-variable onset, may be acute
-pain may become worse w/ mvt
-pain often improves w/ rest
what is HLA-B27?
a gene that is most associated with spondyloarthropathies
what is axial pain?
pain in the lower back region
what are the clinical symptoms of spondyloarthropathies?
-nocturnal pain (NB alternating buttock pain)
-early morning stiffness for more than 30 mins
-positive response to NSAIDS
-no improvement w/ rest
-tendon and joint pain
-often family history
-may also report fatigue, malaise and low grade fever
what is ankylosing spondylitis?
-inflammatory joint arthritis primarily affecting the spine and the sacroiliac joints
-male more common than female
describe the pathology of ankylosing spondylitis
-inflammation of the synovial and cartilaginous joints followed by partial or complete fusion of the joints
what is syndesmophytes?
-reactive bone formation bridging between vertebral bodies
what is enthesitis?
-inflammation where the tendon or ligament meets the bone
where is enthesitis common?
-achilles
-plantar fascia
-patella
-gluteal
what is uveitis?
when the middle layer of the eye (urea) becomes red and swollen
what are the different outcome measures for ankylosing spondylitis ?
-BASDAI
-ASDAS-CRP
-ASAP app