Spleen Flashcards
Although the spleen is located near the stomach it plays no part in _____.
digestion
The spleen is elongate-_____ in shape and of a dull _____ color.
oval
purplish
The spleen is a _____ organ that lies _____ the stomach, high up on the left side of the abdomen, on a level with the 9 to 11 ribs.
lymphatic
behind
The spleen is similar to a _____ in shape and structure but is much _____.
lymph node
larger
The spleen is the largest _____ organ in the body.
lymphatic
The spleen is a _____ organ that filters damaged cells and delivers _____ to the immune system.
peritoneal
antigens
The spleen of an adult human:
1) Weighs about _____ (_____)
2) Is ___-___ ( ___- ___ ) long
3) Is _____ (_____) wide
4) Is _____ (_____) thick.
170 grams (6 ounces)
13-15 cm (5-6 inches) long*
7.5 cm (3 inches) wide
4cm (1.5 inches) thick
*Jennifer says up to 12 cm is the common healthy size
The _____ brings blood to the spleen from the heart.
splenic artery
The splenic artery enters the spleen through a fissure called the _____ and divides into numerous branches, assuming an appearance rather like a _____; they are sometimes called the _____ arteries.
hilum
brush
brush
Blood leaves the spleen through the _____, which becomes part of the _____ that carries the blood to the liver.
splenic vein
MPV
The spleen consists of two types of tissue called _____ and _____.
white pulp
red pulp
The white pulp of the spleen is lymphatic tissue consisting mainly of _____ around the _____.
lymphocytes
arteries
The red pulp consists of venous _____ (cavities) filled with blood and cords of _____ cells, such as _____ and _____.
sinuses
lymphatic
lymphocytes
macrophages
The normal spleen:
_____ (increases/decreases) in size and weight with advancing age.
_____ (increases/decreases) in volume while digestion is in progress, and returns to its normal size when it’s finished.
The size can vary in size in accordance with the _____ status of the body.
decreases
increases
nutritional
The spleen filters blood in much the way that the lymph nodes filter _____. Lymphocytes in the spleen react to _____ in the blood and attempt to destroy them. _____ then engulf the resulting debris, the damaged _____, and the other large particles.
lymph
pathogens
macrophages
cells
The spleen, along with the liver, removes old and damaged _____ from the circulating blood.
erythrocytes (RBCs)
The spleen can also, like _____, produce new red blood cells. It can accordingly be regarded both as a _____ and as a _____ organ.
bone marrow
hemolytic
hemopoietic
The terms hemolytic and hemopoietic come from the Greek: hema: _____; luein: _____; poiein: _____.
blood
to dissolve/destroy
to produce
T or F? The spleen is removable.
true
In healthy people, the spleen plays a role in immunity against _____.
bacterial infections
The shape of the spleen is _____ (adjective).
variable
The spleen consists of 2 components at the hilum:
superomedial component
inferolateral component
In the TRV plane, the superior part of the spleen has a typical fat _____ shape.
comma
In the coronal plane, the spleen has a _____ shape.
inverted comma
Why do we scan the spleen coronally?
Because the stomach is anterior to the spleen and is full of air, which makes it impossible to see through.
The diaphragm cradles the spleen _____, _____, and _____.
posteriorly
superiorly
laterally
If the _____ lobe of the liver is large, it may extend into the LUQ, _____ to the spleen.
left
superior
The fundus of the stomach is _____ and _____ to the splenic hilum.
medial
anterior
The pancreas tail lies _____ to the stomach and is also _____ and _____ to the splenic hilum.
posterior
medial
anterior
What are the 3 organs/parts that are medial and anterior to the splenic hilum?
stomach
pancreatic tail
lesser sac
The left kidney generally lies _____ and _____ to the spleen.
medial
inferior
Why perform an ultrasound on the spleen? (4)
To demonstrate:
- existence of a mass and its composition
- disruption of splenic texture or outline
- spleen size
- progressive changes in masses
Enlargement of the spleen is >_____.
12cm
What does splenomegaly demonstrate?
it is not a disease in itself but a sign of an underlying disorder
Mild-to-moderate splenomegaly is usually caused by: (3)
infection
portal HTN
AIDS
Marked splenomegaly is usually the result of: (3)
leukemia
lymphoma
infectious mononucleosis
Massive splenomegaly is seen in _____.
myelofibrosis
What is myelofibrosis?
the body making too much scar tissue
What is the most frequently observed abnormality of the spleen?
splenomegaly
What are 5 common causes of splenomegaly?
congestive hematologic infiltrative metabolic trauma
The congestive (can’t keep up with its job in the body) cause of splenomegaly is secondary to _____ due to _____. An example is _____.
portal HTN
cirrhosis
anemia
The main hematologic cause of splenomegaly is
polycythemia vera
What is a blood disorder that results in uncontrollable RBC production?
polycythemia vera
Besides splenomegaly, what else does polycythemia vera cause? (2)
hyperviscosity
hypercoagulation
The infiltrative cause of splenomegaly is due to _____ and both types of _____ ( _____ and _____).
leukemia
lymphoma (Hodgkins and non-Hodgkins)
The splenic parenchyma is extremely _____ (homogeneous/heterogeneous) with uniform mid-to-low level _____. It is generally considered that the liver is more _____ (echogenicity) than the spleen, but the spleen parenchyma actually has a _____ echogenicity than the liver (due to its _____ content) or may be _____ (echogenicity) to the liver.
homogeneous echoes echogenic higher water isoechoic
_____ is a common primary malignancy of the spleen, usually appearing as diffuse _____ organ _____. Less common forms include a round _____ mass or multiple _____. Splenic involvement is more common with _____ lymphoma than with _____ lymphoma.
lymphoma homogeneous enlargement focal small nodules non-Hodgkin Hodgkin
The metabolic cause of splenomegaly is caused by _____ disease and _____ disease.
Gaucher’s
Niemann-Pick
What is Gaucher’s disease?
a disease where there is a missing fat enzyme
What is the disease that means the body has too much sphingomyelin?
Niemann-Pick
Gaucher’s Disease
It is _____ (inherited/not inherited).
It means the body is missing a _____ enzyme.
_____ is one of the earliest signs.
inherited
fat
splenomegaly
Niemann-Pick Disease
It is _____ (inherited/not inherited).
It means the body has too many deposits of _____.
inherited
sphingomyelin
What are the signs and symptoms of splenomegaly?
LUQ pain
pressure on adjacent organs
What causes LUQ pain with splenomegaly?
the stretching of the capsule or ligament of the spleen
This mass appears as an echo-free areas with smooth, sharp borders and acoustic enhancement.
cyst
The 4 categories of cysts on the spleen are
infectious
post-traumatic
primary congenital (born with it)
intrasplenic pancreatic pseudocyst
Infection or parasitic cysts may be caused by _____ or _____.
hydatid cysts
echinococcus
How is an infectious or parasitic cyst identified among the different kinds of cysts?
calcification in the wall
What is needed to be diagnostic for infectious/parasitic cysts? (2)
percutaneous aspiration
history and background info
Hydatid cysts result from a _____.
parasitic tapeworm