Liver Abnormalities Flashcards
_____ of the liver is incompatible with life (not having one).
Agenesis
Often, with agenesis of the RLL, the _____ lobe is also absent.
caudate
T or F? With agenesis, compensatory hypertrophy of the remaining lobes normally occurs and the LFTs are normal.
True
This position abnormality is when the liver is found in the left hypochondrium.
situs inversus totalis
In congenital diaphragmatic hernias or omphalocele, varying amounts of liver may herniate into the _____ or outside the _____ cavity.
thorax
abdominal
If someone has kidney cysts, they probably have _____ cysts too.
liver
T or F? Kidney cysts are more common than liver cysts.
True
Liver cysts occurrence increases past the age of _____.
80
Benign hepatic cysts are _____ (echogenicity) with well-demarcated _____ (thickness) walls and posterior acoustic enhancement.
anechoic
thin
Is active intervention of cysts recommended in patients without symptoms?
No
Occasionally, the patient may develop pain and fever secondary to cyst hemorrhage or infection. In this case, the cyst may contain internal _____ and _____, a _____ wall, or may appear _____ .
echoes
septations
thickened
solid
T or F? Cyst ablation with alcohol can be performed using U/S guidance.
True
Rather than ablation with alcohol, what is another treatment for cysts?
surgical excision
A hemorrhagic liver cyst will appear as a cyst with _____ _____, accompanied by (2)
internal echoes
acute RUQ pain
decreased hematocrit
If you see cysts in the kidneys, always check the _____ for cysts as well.
liver
The adult form of _____ _____ disease is inherited in an autosomal dominant pattern. The frequency with liver cysts in association with this disease is high.
polycystic kidney disease
_____ is a term for liver inflammation due to viruses or toxins.
Hepatitis
Hepatitis is _____ when it lasts for less than 6 months.
acute
This kind of hepatitis is more likely to be asymptomatic in younger people. The convalescent stage is 7 to 10 days, with the total illness lasting 2 to 6 weeks.
acute viral hepatitis
If you see a hypoechoic liver parenchyma, hepatomegaly, and hyperechoic PV walls, this is a sign of
acute hepatitis
This hepatitis shows diffuse swelling of the hepatocytes, proliferation of Kupffer cells, and infiltration of the portal areas by lymphocytes and monocytes.
acute hepatitis
More specific symptoms of acute hepatitis are (6)
profound loss of appetite aversion to smoking (in smokers) dark urine yellowing of the eyes jaundice abdominal discomfort
These 2 symptoms of the most common presenting symptoms of acute hepatitis.
jaundice
hepatomegaly
What are the 6 kinds of hepatits?
A B C D E G
Hepatitis A is also called
infectious jaundice
Hepatitis A is transferred by what route?
fecal-oral
Does Hepatitis A have an acute and chronic stage?
No, just acute
Hepatitis A occurs most frequently in _____ world countries. There is a vaccine that prevents it for up to _____ years. People with Hep A are advised to _____, _____, _____ . Hep A can spread through consumption of raw sea food or contaminated _____ .
third 10 rest stay hydrated avoid alcohol water
Which hepatitis is the least serious?
A
The combination of these two forms of hepatitis can cause a _____, and even without cirrhosis, leading to a life-threatening form of fulminant hepatitis.
Hep A and Hep C
superinfection
Does Hep B have both acute and chronic versions?
yes
A vaccine for Hep B exists that prevents infection for how long?
life
This form of hepatitis can lead to hepatocellular carcinoma.
Hep B
The methods of transmission for Hep B are
blood and body fluids
Symptoms of this kind of hepatitis occur long after the initial infection, around 4 to 24 weeks and patients may not even experience them. The pain can resemble arthritis, affecting specific joints and accompanied by redness and swelling.
Hep B
5-10% of people with Hep B eventually develop
cirrhosis
Hep B poses a risk for _____ cancer.
liver
Hep C is also called
Non-A/Non-B
This is the most common blood-borne infection.
Hep C
People can get this type of hepatitis from inadequately sterilized medical or dental equipment.
Hep C
Hep C is spread by contact with
infected human blood
T or F? Hep C can be passed from an infected mother to her baby during birth.
True
Does breastfeeding increase transmission of Hep C?
No
Before 1990, Hep C was primarily transmitted by
blood transfusions
Most patients with Hep C _____ (do/do not) experience symptoms.
do not
If someone experiences symptoms from Hep C, it is often after _____ months of infection.
12
Chronic hepatitis C can be present for _____ - _____ years, and _____ or _____ can sometimes develop before patients experience any clear symptom.
10-30 years
cirrhosis
liver failure
Nearly 40% of liver transplant patients are infected with Hep _____.
C
Is liver transplantation a cure for Hep C?
No
This kind of hepatitis is only dangerous if you also have Hep B.
Hep D
Hep D is also called
hepatitis delta virus
T or F? Hep D was discovered as an antigen in Hep B virus by Dr. Mario Rizzetto in 1977.
True
Hep D is an uncommon infection in North America, but the people who are primarily infected are
IV drug users
How is Hep D spread?
thought to be similar to Hep B, blood
possibly sexual transmission
Is there any specific treatment for Hep D? But what is a possible alternative-type treatment that has been used in the past with some success? And what is another possible treatment?
No
High dose of interferon given for over 12 years
orthotopic liver transplant
Persistence of biochemical abnormalities beyond 6 months is
chronic hepatitis
What is the sonographic appearance of chronic hepatitis?
hyperechoic parenchyma
small, shrunken liver
decreased echogenecity of PV walls
(opposite of acute hepatitis)
Abscesses = ? and ?
leukocytosis
fever
This is a puss-filled area in the liver.
Pyogenic liver abcess
What are some of the causes of liver abscesses?
- Abdominal infection such as appendicitis, diverticulitis, or a perforated bowel
- Infection in the blood
- Infection of the liver secretion (biliary) tract
- Recent endoscopy of the biliary system
- Trauma that damages the liver
The most common presenting features of pyogenic liver abscess are:
Chalk-colored stool Dark urine Fever, chills, leukocytosis Loss of appetite Nausea, vomiting Pain in right upper abdomen (more common) or throughout the abdomen (less common) Unintentional weight loss Weakness Yellow skin (jaundice)
Pyogenic liver abscesses most commonly occur in the ______ lobe.
right lobe
How do pyogenic liver abscesses reach the liver (4)?
Bile ducts
PVs
HAs
lymphatic channels
Varied appearances of pyogenic liver abscesses are:
There is “air” within the abscess
Purulent abscesses appear cystic with the fluid ranging from echofree to highly echogenic
Early suppuration may appear solid with altered echogenicity, usually hypoechoic
The abscess wall can vary from well-defined to irregular and thick
Gas-producing organisms give rise to echogenic foci with a posterior reverberation artifact.
For true diagnosis of pyogenic liver abscesses, what must be done?
aspirate the abscess
Treatment for pyogenic liver abscesses is
surgery
draining the abscess
along with this procedure, you will receive long-term antibiotic therapy (usually 4 - 6 weeks).
sometimes antibiotics alone can cure the infection
With pyogenic liver abscesses, what life-threatening condition could develop?
sepsis
Even with treatment, pyogenic liver abscesses can be life-threatening in _____% to _____% of patients.
10% - 30%
When you hear “air in the abscess”, you should automatically think
pyogenic liver abscess
This is a liver infection that occurs when a parasite that came from the intestines reaches the liver, and travels through the portal vein.
amebic abscess
This is the most common extraintestinal complication of amoebic dysentery
amebic abscess
Transmission of amebic abscess is by the _____-_____ route. The most common bacterial agent related to this is ______.
fecal-oral
e-coli
The most common presenting symptoms of amebic abscess are
right upper quadrant pain
diarrhea
Sonographic signs of amebic abscesses are (7)
Round or oval-shaped lesion
Absence of a prominent abscess wall
Hypoechoic compared to a normal liver
Fine low-level internal echoes
Distal enhancement
Contiguity with the diaphragm/liver capsule
Typically occurs in the dome of the liver (RLL)
T or F? For amebic abscesses, amebicidal drugs are effective and symptoms improve by 24-48 hours but complete resolution of the abscess varies from 1.5 – 23 months with a median of 7 months.
True
Possible dangerous risks of amebic abscesses are
may rupture into the abdominal cavity, the lining of the lungs, the lungs, or the sac around the heart
could spread to the brain
This is a mycotic (fungal) infection of the blood that results in small abscesses in the liver. The appearance of these lesions can change over the course of the disease process.
candidiasis
The ultrasonic appearance of Candida infection in the livers of immunosuppressed patients is quite characteristic:
“Wheel Within A Wheel”: a lesion with a peripheral hypoechoic zone, an inner echogenic wheel and a hypoechoic center. This is the earliest manifestation of a fungal infection and the most recognizable.
After some time, later the “wheel within a wheel” turns into a “______” appearance when the hypoechoic center ______.
It will then turn into a(n) uniformly ______ (echogenecity) focus and then a(n) ______ (echogenecity) focus representing scar formation.
“bullseye”
calcifies
hypoechoic
echogenic
What is the most common cause of hydatid disease?
echinococcal cyst