Liver Flashcards
What is the largest parenchymal organ in the body?
Liver
What does parenchymal mean?
has tissue
The primitive gut is formed during the _____ week of embryonic life and is composed of these 3 parts:
4th
Foregut
Midgut
Hindgut
The _____ veins bring oxygenated blood from the embryonic portion of the placenta to the embryonic heart.
umbilical veins
The _____ veins return blood from the yolk sac to the heart.
vitelline veins
Vitelline veins eventually become what vessels?
portal veins
The liver comes from what part of the primitive gut?
the foregut
In prenatal live, oxygenated blood from the placenta is carried by the _____ _____ vein and _____ _____ to the IVC and _____ atrium.
left umbilical vein
ductus venosus
right atrium
List the various liver structures (6)
1) portal veins
2) hepatic veins
3) arteries
4) ducts
5) hepatic ligaments
6) hepatic fissures
The liver tissue sequentially moves into the _____ veins and then the _____ veins.
vitelline veins
umbilical veins
As the liver tissue moves into the vitelline veins, their midsection becomes _____, whereas their _____ ends become the _____ _____ veins and their _____ ends become the _____ _____ veins.
capillarized
caudal ends become the primitive portal veins
cranial ends become the early hepatic veins
After the right umbilical vein and part of the left umbilical vein degenerate during fetal development, the remaining left umbilical vein carries all the blood from the _____ to the _____.
placenta
fetus
An umbilical cord should contain _____ arter(ies) and _____ vein(s).
2 arteries
1 vein
The ductus venosus develops as a large shunt within the liver and allows blood to connect from the _____ _____ to the baby’s _____, by bypassing the _____.
umbilical cord
heart (right side)
liver
Direction of fetal circulation:
Umbilical Vein (ligamentum teres) l l \/ ? l l \/ ? (AKA ?) l l \/ ?
Umbilical Vein (ligamentum teres) l l \/ Left Portal Vein l l \/ Ductus Venosus (AKA Ligamentum Venosum) l l \/ IVC
The _____ _____ closes shortly after birth, when the umbilical cord is cut and blood flowing between the mother and fetus stops.
ductus venosus
The _____ _____ is a remnant of the ductus venosus. It runs from the _____ to the _____, separating the left LLL from the caudate lobe of the liver.
ligamentum venosum
LPV
IVC
The liver is covered by a thin connective tissue called
Glisson’s capsule
Glisson’s capsule covers the entire liver except the “_____ _____” near the dome of the liver, on the posterior surface of the RLL.
“bare area”
Glisson’s capsule is at its thickest around the _____ and the _____.
IVC
porta hepatis
These macrophages remove bacteria, foreign matter and weakened blood cells from the liver sinusoids (blood in the sinusoids).
Kupffer cells
T or F? Kupffer cells are around at all times, they just “hang out” if no infection.
True
The hepatic parenchyma is composed of _____ (type of cell) dispersed with Kupffer cells and organized into lobules approximately 1 x 2 mm in size.
hepatocytes
Typically about _____ million of these are found in the liver, and they are the functional units of the liver.
1 million
lobules
The liver occupies a major portion of the _____ _____ (region of abdomen).
right hypochondrium
Inferiorly, the liver extends into the
epigastrium
Laterally, the liver extends into the
left hypochondrium
Superiorly, the liver extends into the
dome of the diaphragm
Posteriorly, the liver borders the
bony lumbar region of the muscular posterior abdominal wall
The 5 main liver functions are
1) Bile drainage
2) Blood glucose regulation
3) Synthesis/Storage of amino acids, proteins, vitamins, and fats
4) Detoxification
5) Blood circulation/filtration
Bile from the liver travels down the _____ and joins with the bile from the _____ and ends in the _____ head.
CBD
GB
pancreatic head
The liver is a(n) _____ (location in body) structure situated in the _____ upper quadrant of the abdomen.
intraperitoneal
right
What portions of the liver are in contact with the diaphragm?
superior
anterior
part of the posterior
The caudate lobe, which is the smallest lobe, is marked on the _____ border by the _____ surface of the LPV and the _____ border is the _____.
anterior border
posterior surface
posterior border
IVC
The posterior surface of the right lobe of the liver is indented by the _____.
right kidney
The IVC lies _____ to the liver and has a short _____ course just before entering the right atrium of the heart.
posterior
intrahepatic
The LLL lies adjacent to the body of the pancreas, _____, and _____, and lies close to the body and _____ of the stomach.
SV
SA
antrum
The blood received by the liver from the PV delivers nutrients just absorbed from the _____.
intestines
Oxygenated (and some deoxygenated) blood is brought to the liver by the _____ and ______.
PVs
HAs
Hepatic sinusoids are similar to what other vascular structure we have learned about?
capillaries
Central veins connect to _____ veins, which then connect to the _____.
hepatic
IVC
What allows blood from the HAs and PV to mix in the liver?
HAs and PV deliver blood to the tiny hepatic sinusoids and is eventually delivered to the HVs, which conduct blood toward the heart.
Blood from the liver sinusoids is eventually deliver to the _____ veins, which conduct blood toward the _____.
hepatic veins
heart
The average adult liver is _____ grams.
1500
Liver size depends on the _____ segment of the _____ (lobe) and the length of the _____.
lateral
LLL
RLL
Hepatomegaly is indicated with a superior-inferior dimension of >____cm or when the RLL extends inferior to the _____ _____ of the _____ kidney.
15
lower pole
right
Liver echogenicity is usually _____ (heterogeneous/homogeneous) and is slightly _____ (echogenicity) compared to the normal renal cortex.
homogeneous
hyperechoic
T or F? The LLL is always smaller than the RLL.
True
If the LLL is congenitally small or atrophic, it may be a result of interference with the _____ supply when the _____ _____ closes at birth.
LPV
ductus venosus
The longer the RLL, the _____ (less/more) likely the interference of bowel gas by the hepatic flexure.
less
The length of the _____ (lobe) determines the clarity of the right kidney in the supine position.
RLL
A tongue-like projection of the RLL that may extend to the iliac crest.
Reidel’s Lobe