spinal reflexes Flashcards
lower motor neuron
motor neuron that has cell body in ventral horn.
upper motor neuron
nerve cells that are higher in the brain and send axons down the spinal cord in descending tracts, synapsing with dendrites of the lower motor neurons.
motor unit
smallest unit of contraction
motor neurone together with its cell body in the dorsal horn, its motor axon and set of muscle fibres that it innervates
how is a twitch generated
single AP contracts one motor unit.
Tetanic Contraction
smooth contraction: initiated by a train of action potentials at high frequency
is tetanic contraction healthy
yes
how is a fused contraction produced
tetanic fusion frequency
which type of fibres have all or nothing activity
motor
how are muscles for fine control different to other muscles
more small motor units
Pyramidal System
upper motor neurone cell bodies: project directly from frontal lobe (mainly motor cortex) to spinal cord. They travel via the corticospinal tract.
Extrapyramidal System
Upper motor neurone cells travel to the brainstem, synapse, and then project to the spinal cord. These are regulated by the motor cortex.
reflex
Involuntary motor action triggered by a sensory input
where are reflexes stored
dorsal and ventral grey matter in forms of patterns of synaptic connections
monosynaptic reflex
reflex with no interneurons neurons between muscle spindle afferent and motorneuron efferent
homonymous reflex
muscle sending sensory information is the one that contracts
reciprocal inhibition
1 muscle contracts, another relaxes
which muscle contracts when patella tapped
quadriceps
hamstrings relax
proprioceptor/muscle spindle
Receptor that mediates tendon reflexes
what makes up a proprioceptor/muscle spindle
stretch receptor inside a connective tissue sheath
what is the main sensory nerve fibre from muscle spindle
la afferent
what do muscle spindles detect
muscle length
how many muscle spindle Ia nerve fibre synapses must be active to fire a motor neurone
2+
what does a single Ia sensory nerve fibre produce in a motor neuron
Excitatory post-synaptic potential
Spatial Summation
Two synaptic inputs are active at the same time and the EPSPS are summed together
Temporal Summation
single Ia nerve fibre fires a high frequency burst of action potentials so that the EPSPs sum together to trigger an action potential.
what is a muscle spindle made up of
modified skeletal muscle fibres with contractile tissue at the end and the centre of the spindle with no actin or myosin
what type of motor neuron supplies a muscle spindle
gamma motor neuron
how does the brain keep muscle spindle feedback at the right level during movement
activates both alpha and gamma motor neurons
how is constant muscle length maintained despite fatigue
muscle spindles give continuous feedback to motor neurons and continually adjust the motor neuron output during normal movement
mechanism of maintaining muscle length despite fatigue
Holding something: initially there is input to motor neurons from descending axons and from muscle spindle Ia afferents. The combined input keeps it in positon.
However, biceps fatigue after a while: they contract less strongly and start to stretch. This stretch increases the activity of the muscle spindles, which increases input to biceps motor neurons as well as spinal cord
Increased contraction: arm moves back into place.
golgi tendon organ
Second major proprioceptor.
what activates golgi tenson organ
tension
what does golgi tendon organ do
Prevents muscles from contracting too strongly
what type of motor neuron does golgi tendon organ connect to
glycinergic inhibitory neuron
what activates a flexion relfex
activation of small myelinated nociceptor afferents
are flexor reflexes polysynaptic or monosynaptic
polysynaptic
what type of reflex can the brain supress
polysynaptic
what is a crossed extensor reflex
Activation of extensors in the other leg during flexion reflex to take weight
how are crossed extensor reflexes produced
afferent fibres cross stimulated side of body to contralateral side of spinal cord. There they synapse with interneuron
muscle tone
small amount of contraction in muscles when these are moved passively
what does lower motor neuron damage cause
flaccid paralysis - decr tone, paralysed muscles
what does upper motor neuron damage cause
spasticity - incr tone