neurotransmission

Question 1

End Plate Potentials

Answer 1

Depolarization of skeletal muscle fibres: caused by neurotransmitters binding to the postsynaptic membrane in the neuromuscular junction.

Question 2

Miniature End Plate Potentials

Answer 2

small depolarizations of the postsynaptic membrane caused by the release of a single vesicle into the synaptic cleft. This release of neurotransmitters is without a signal from the axon. However, no action potential is fired as these small depolarizations do not reach the threshold

Question 3

Main Neurotransmitters

Answer 3

glutamate (primary sensory neuron), acetylcholine, glutamate, GABA (inhibitory), Glycine (inhibitory), noradrenaline, dopamine

Question 4

Neuromodulators

Answer 4

Physiological process by which a neuron uses one or more chemicals to regulate diverse populations of neurons

Question 5

neuromodulator examples

Answer 5

Noradrenaline
Dopamine
Acetylcholine, glutamate, GABA

Question 6

what receptors do neuromodulators activate

Answer 6

G protein coupled receptors

Question 7

what receptors are involved in fast neurotransmission

Answer 7

direct gating of ion channel

Question 8

what does NT release cause in the CNS in post synaptic cells

Answer 8

EPSPs and IPSPs

Question 9

EPSP

Answer 9

Acetylcholine binds to nicotinic Ach receptor (permeable to Na+ and K+ ions). It depolarizes the membrane from negative to positive. Two Ach molecules are required (for influx of Na+)

Question 10

IPSP

Answer 10

The receptor (often a GABA receptor) that inhibits Aps is not permeable to cations but to CL. The movement of Cl- causes the membrane to become more negative (stabilizes it, stops production of AP)

Question 11

what does acetylcholinesterase do

Answer 11

breaks down Ach