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Patient Care > Spectrum of Activity Abx > Flashcards

Spectrum of Activity Abx Flashcards

1
Q

What antibiotics cover atypicals?

A 
"DAFT"
•     Doxycycline
•     Azithromycin (Zithromax)
•	FQs: (L and M: good; C: moderate) 
•     Tygacil
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2
Q

What antibiotics cover anaerobes?

A 
"Z-FACT"
•     Zosyn
•     Flagyl
•	Avelox and ampicillin/sulbactam 
•	Clindamycin and carbapenems 
•     Tygacil
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3
Q

What antibiotics cover pseudomonas?

A 
"GAZe into the C"
Gentamicin
Aztreonam
Zosyn
except Ertie

Carbapenems
Ceftazidime
Cefepime
Cipro

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4
Q

Which gram (-) bugs do 3rd generation cephalosporins cover?

A 
Gram Negatives covered: “HeN PEcK”
	H. flu
	Nisseria
	Proteus
	E. coli
	Klebsiella
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5
Q

Which gram (-) bugs do 1st generation cephalosporins cover?

A

PEcK → proteus, E. coli, klebsiella

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6
Q

Nafcillin

A 
most gram (+) aerobes
(NOT MRSA or enterococcus)
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7
Q

Ampicillin/Sulbactam

A
  • cover most gram (+) aerobes including enterococcus but not MRSA
  • covers most gram (-) aerobes (NOT pseudomonas)
  • covers anaerobes
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8
Q

Which drug has good activity against Acinetobacter baumannii, a high drug-resistant GNR?

A

Ampicillin/Sulbactam

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9
Q

Zosyn

A

most gram (+) aerobes including enterococcus (NOT MRSA), covers most gram (-) aerobes including pseudomonas, also covers anaerobes

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10
Q

Keflex and Ancef

A

Covers most Gram (+) and (-) aerobes
• Gram (-): PEcK → proteus, E. coli, klebsiella

Does NOT cover MRSA, enterococcus or pseudomonas

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11
Q

Cefuroxime (Ceftin)

A

Cover most Gram (+) and (-) aerobes

Does NOT cover MRSA, enterococcus or pseudomonas

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12
Q

Ceftriaxone

A
  • cover most gram (+) aerobes (not including enterococcus or MRSA)
  • covers most gram (-) aerobes (NOT pseudomonas)
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13
Q

Cefotaxime

A
  • cover most gram (+) aerobes (not including enterococcus or MRSA)
  • covers most gram (-) aerobes (NOT pseudomonas)
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14
Q

Ceftazidime

A

covers most gram (-) aerobes (including pseudomonas!)

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15
Q

cefepime

A

 cover most gram (+) aerobes (not including enterococcus or MRSA)
 covers most gram (-) aerobes (including pseudomonas)

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16
Q

Ceftaroline fosamil

A

Cover most Gram (+) aerobes
o Covers MRSA
o Does NOT cover enterococcus

17
Q

Carbapenems

A
  • Gram (+) aerobes (enterococcus except Ertie)
  • Gram (-) aerobes (pseudomonas except ertie)
  • anaerobes!
  • None cover MRSA
18
Q

Aztreonam (Azactam)

A

covers most gram (-) aerobes (including pseudomonas)

19
Q

Vancomycin

A

MRSA!!!

gram (+) [including MRSA & enterococcus]; oral form covers C. diff

20
Q

Telavancin

A

gram (+) [including MRSA & enterococcus]

21
Q

Daptomycin

A

gram (+) [including MRSA & enterococcus]

22
Q

Clindamycin

A

gram (+) [including MRSA, but NOT enterococcus]; covers anaerobes

23
Q

Azithromycin

A

covers most gram (+) aerobes (not including enterococcus or MRSA)

covers some gram (-) aerobes (does not cover pseudomonas)

  • only covers gram (-) found in the respiratory track (H. Flu, M. Cat)
  • does NOT cover e.coli, proteus, etc.

    covers atypicals
24
Q

Flagyl

A

Anaerobes (poor enterococcus coverage)

25
Q

Bactrim

A

gram (+) aerobes [including MRSA]
• Does not cover enterococcus

gram (-) aerobes (except pseudomonas)

26
Q

Cipro

A

o does NOT cover most gram (+) aerobes but covers enterococcus in the urine
o covers MOST gram (-) aerobes and PSEUDOMONAS

27
Q

Levaquin

A

does NOT cover most gram (+) aerobes but covers enterococcus in the urine

covers MOST gram (-) aerobes (pseudomonal coverage is debatable)

Atypicals (good coverage)

28
Q

Avelox

A

o covers most gram (+) aerobes but does not cover enterococcus
o covers MOST gram (-) aerobes (does NOT cover pseudomonas)
o covers atypicals
o Moxifloxacin has moderate coverage of anaerobes

29
Q

Rifampin

A

MRSA

30
Q

Doxycycline

A

covers gram (+) aerobes including MRSA, but not enterococcus

covers atypicals

31
Q

Tigacycline

A

covers gram (+) aerobes including MRSA & enterococcus

covers most gram (-) aerobes (NOT pseudomonas)

also covers anaerobes and atypicals

(EVERYTHING but pseudomonas)

32
Q

Gentamicin

A

Gram NEGATIVES

covers most gram (-) aerobes including pseudomonas; if combined with a ß-lactam, gent can help cover most Gram (+) aerobes, including enterococcus (does not cover MRSA)

Patient Care (5 decks)

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