Special Senses Flashcards

1
Q

What is sound

A

Compressive air wave that travels at 343m/s in air

Ear detects sound as vibrations and converts to electrical signals to be processes as sound

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2
Q

What is frequency

A

Number of wave cycles per second, in Hz

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3
Q

What is volume

A

Loudness of sound relative to threshold (sound just audible), in decibels

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4
Q

What is cochlea

A

Part of inner ear responsible for hearing

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5
Q

What are the parts of cochlea

A

Bony labyrinth
Membranous labyrinth
Organ of Corti

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6
Q

What is bony labyrinth

A

Bony canal in petrous part of temporal bone, containing perilymph and surrounding membranous labyrinth
In cochlea it forms the cochlear canal

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7
Q

What is membranous labyrinth

A

Duct suspended in perilymph in bony labyrinth, containing endolymph
In cochlea forms cochlear duct

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8
Q

Describe structure of cochlear duct

A

Bounded by Reissner’s Membrane, basilar Membrane
Contains endolymph
Contains Organ of Corti
It separates cochlear duct into Scala vestibuli and scala tympani superiorly and inferiorly

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9
Q

Describe structure of Organ of Corti

A

It is the part of inner ear responsible for detecting sound, composed of epithelial hair cells on basilar membrane and tectorial membrane that hair cells interact with

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10
Q

What do hair cells do

A

Hair cells are epithelial cells on basilar membrane with sterocilia

Inner hair cells: have sterocilia that move relative to endolymph, detect sound
1 row

Outer hair cells: have sterocilia embedded in tectorial membrane, detect amplitude of sound by relative movement of basilar membrane against tectorial membrane
3 Rows

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11
Q

How is sound wave conducted in inner ear

A

Vibrations from middle ear pass through oval window to scala vestibuli, scala tympani, out through round window

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12
Q

How are vibrations in inner ear converted to electrical signals

A
  1. Vibrations of perilymph cause movement of basilar membrane
  2. Leads to movement of stererocilia: IHC relative to endolymph, OHC relative to tectorial membrane
  3. Bending of sterocilia cause influx of K+ into cell
  4. Depolarisation causes influx of Ca by VOCC
  5. Increased [Ca2+] triggers neurotransmitter release
  6. Neurotransmitter triggers AP in spiral ganglion neurones
  7. AP transmitted down spiral ganglion neurones to CN VIII
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13
Q

What is tonotopy

A

Point-for- point Representation of specific sound frequencies on specific regions of primary auditory cortex

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14
Q

How are different frequencies detected

A

Different regions of basilar membrane have different frequencies
Frequency decreases down length of BM
Hair cells at specific regions transmit signals about specific frequencies

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15
Q

Describe the auditory pathway

A
  1. Spiral ganglion cells form form cochlear part of CN VIII
  2. Cn viii travel in internal acoustic meatus and divide into cochlear/vestibular nerve at level of medulla
  3. SGN synapse with second order neurones in cochlear nucleus in medulla
  4. SON synapse in: A. Superior olivary complex in medulla and ascend in lateral meniscus
    or B. Inferior colliculi in midbrain
  5. From inferior colliculi axons project to medial geniculate nucleus in Thalamus
  6. From thalamus axons project to auditory cortex in superior temporal gyrus
  7. TON project to primary auditory cortex in superior temporal gyrus
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16
Q

What is the role of superior olivary complex

A

Localisation of sound:
Detects differences in amplitude & timing of arrival of sound between two ears
Thus localisation requires both ears to be functioning

17
Q

How do you assess hearing

A

Visual - otoscope
Rinne’s - conduction
Weber’s - localisation
Audiogram - sensitivity against frequency

18
Q

Causes of conductive hearing loss

A

Ruptured TM
Otitis media
Otosclerosis (progressive immobilisation of oscicles)

19
Q

Causes of sensory hearing loss

A

Hair cell damage: loud noise, trauma

Hair cell death: ototoxic Drugs

20
Q

Causes of neural hearing loss

A

Spiral ganglion damage - Acoustic neuroma
Tinnitus
Old age
Auditory neuropathy - hyperbilirubinaemia