special circulations Flashcards
what is the blood supply to the lungs
2 circulations
bronchial circulation- part of systemic circulation , meets the metabolic requirements of parts of the lungs
pulmonary circulation- blood supply to alveoli, required for gas exchange
features of pulmonary circulation
must accept the entire cardiac output
works at low pressure and resistance
adaptations to promote efficient gas exchange
high density of capillaries in alveolar wall so large surface area
short diffusion distance as there is a thin layer of tissue separating gas phase from plasma.
what is hypoxic pulmonary vasoconstriction
mechanisms where vascular smooth muscle constricts when there is a relatively low oxygen level.
vasoconstriction of pulmonary vessels reduces blood supply to the hypoxic region of lungs to maintain ventilation perfusion ratio.
in systemic circulation this is the complete opposite as capillaries would dilate in response to hypoxia.
downside of chronic hypoxia
leads to chronic vasoconstriction which will increase vascular resistance which leads to chronic pulmonary hypertension making it more difficult for right ventricle to pump out blood and can lead to right ventricular heart failure.
in the upright position how is the hydrostatic pressure on vessels in the lungs
greater hydrostatic pressure on vessels in the lower part of the lung ( base) than at the apex
effects of exercise on pulmonary blood flow
- increased cardiac output
- small increase in pulmonary arterial pressure.
- opens apical capillaries
- increased o2 uptake lungs
- as blood flow increases capillary transit time is reduced
how is tissue fluid formed
starling forces determine fluid formation
hydrostatic pressure of blood within capillary pushes fluid out of the capillary and oncotic pressure which is exerted by large molecules such as plasma proteins draws fluid into the capillary.
in what clinical conditions can you get pulmonary oedema
mitral valve stenosis
left ventricular failure
how does pulmonary oedema change by posture
forms mainly at bases when upright and throughout lung when lying down.
how to relieve symptoms of pulmonary oedema
diuretics