Sound pathways and Big PIcture stuff/Toris Flashcards
What is the auditory signaling pathway (start from cochlear nerve, so after sound gets through ear etc)?
** note the trapezoid body was drawn in in yellow
-this is another major bilateral crossover point
Turns out the cochlear nuclei fibers decussate in the trapezoid body
What are the 3 places in the auditory signaling pathway that send information bilaterally/crossover?
Trapezoid body
lateral lemniscus commissure
Inferior colliculus commissure
What is the main role for the superior olivary nuclei? (actually 2 roles in different sides of nuclei)
medial division of SON = compare time lag
-this is where it sends olivocochlear bundle to outer hair cells??
Lateral division of SON = compares intensity
Where do endolymph and perilymph live? what is the difference between the two?
bonus for special hidey hole for perilymph
Endolymph is in scala media
-has higher K+, lower Na+
Perilymph is in scala vestibuli & tympani
-has higher Na+, lower K+
Bonus, perilymph also lives in the Tunnel of COrti! (inside scala media.organ of corti)
Where is the primary auditory cortex?
What do the 2 areas of PAC deal with respectively?
Heschl’s gyrus (Brodmans area 41) - transverse temporal gyrus
(lateral part of the PAC deals with low frequency, medial part deals with high frequency)
Name the parts of this picture?
- scala vestibuli
- scala media
- scala tympani
light green = reissners membrane
light yellow = basilar membrane
pale purple blob= organ of corti
light blue = osseous spiral lamina (which also separates SV & ST?)
Describe the conduction of sound through the ear
pinna–>EAM–>TM–>ossicles–>hit oval window–> create vibrations/wave in fluid
the frequency of vibrations through the fluid determines what aspect of sound
frequency = pitch
the amplitude of vibrations through the fluid determines what aspect of sound
intensity (decibels)
Describe the nerve fibers of the organ of corti
they attach to basilar membrane & receive sound conduction
-short fibers are proximal & get HIGH frequncy
-long fibers are distal & get LOW frequency
Where is the tectorial membrane? What does it do?
it sits on top of the hair cells
when endolymph moves, it moves the tectorial membrane and causes move/shearing of hair cells
what are outer hair cells used for? are there a lot or a little of them?
outer hair cells are for fine tuning
there are MANY rows of them
What are inner hair cells used for? are there a lot or a little of them?
Inner = auditory conduction
there is only ONE row of inner hair cells
What runs through the Tunnel of corti?
perilymph (surprise!) and CN VIII fibers
How does tectorial membrane shearing cause sound transduction?
when it shears –>K+/Na+ influx –> release of glutamate
how do the outer hair cells help with sound transduction?
amplify movements of basilar membrane
separate background noise from important signals (remember they are the fine tuners)
*receive input from medial olivocochlear system
What is the vestibule for and what structures does it contain?
It is for balance
it has the utricle & saccule in it, which detect acceleration
what do semicircular canals detect?
rotation of the head
What vessels provide blood supply to the TM?
anterior tympanic artery & stylomastoid branch of posterior auricular artery
What nerves/branches provide sensory innervation of the tM?
external TM = auriculotemporal N (CN V3) & auricular branch of CN X (GSA)
internal = tympanic branch of CN IX (GVA)
What reflex does irritation of the TM cause?
CN X cough reflex
Where does the pharyngotympanic tube open up? be very specific
opens posterior to inferior meatus in the nasopharynx by the levator/tensor veli palatini mm
What provides blood supply to pharyngotympanic tube?
ascending pharyngeal artery and maxillary artery
what provides blood supply to the auricle of the ear?
superficial temporal artery & posterior auricular artery
What provides blood supply to EAM of the ear?
(3 of them)
superficial artery of the superficial temporal artery & posterior auricular artery & deep auricular artery
What provides lymph drainage for the EAM?
deep cervical nodes
what provides lymph drainage from the auricle?
parotid, mastoid and superficial cervical nodes
Can you describe the innervation to the external ear? The answer is a good picture that maybe you can just remember
What is the middle ear/tympanic cavity continuous with?
it is continuous with mastoid air cells and nasopharynx
There are 4 important nerves in the tympanic cavity, can you name them?
Tympanic nervous plexus - sensory to mucosa
-Tympanic branch of CN IX and carotid sympathetic plexus
Chorda tympani (CN VII) - SVA taste, GVE-P submandibular/lingual glands
-Passes between malleus and incus to exit petrotympanic fissure
CN VII - innervation to stapedius m
Lesser petrosal n. - GVE-P from CN IX innervate parotid gland
In the ear, what structures does the surface ectoderm form?
cochlear duct, otic ganglia, semicircular canals
In the ear, what structures does the mesenchyme form?
scala vestibuli
scala tympani
In the ear, what structures do the epithelial cells form?
sensory hair cells
In the ear, what structures do the neural crest cells form?
ear ossicles!!!
In the ear, what structure is made up from the surface ectoderm + mesenchyme + endoderm?
tympanic membrane
Breifly tell me the embryology formation [that occurs week] of some of ear’s important structures
wk 4: otic placode develops
–>becomes otic vesicle
–>becomes statoacoustic ganglia of CN VII & NC cells
-Ventral vesicle => saccule & cochlear duct
-Dorsal vesicle => utricle, semicircular canals, endolymphatic duct
wk 6: cochlear duct formation
wk 7: spiral organ of corti develops
wk 8: 2.5 spirals of cochlea are present
- this might be pretty important*
For pharyngeal arch #1, what are:
a) bones/cartilage it forms
b) nerves it forms
c) pouch
d) cleft
a) Maxilla, mandible, zygomatic, vomer Malleus, incus - inner ear
b) CN V, V2 - maxillary, V3 - mandibular
c) Auditory tube, Middle ear
**TM forms here where pouch/cleft meet
d) EAM
For pharyngeal arch #2, what are:
a) bones/cartilage it forms
b) nerves it forms
c) pouch
d) cleft
a) Styloid process, stylohyoid ligament, lesser horn/superior body of hyoid, Stapes - inner ear
b) CN VII
c) tonsillar sinus & palatine tonsils
d) NOTHING [this closes]
For pharyngeal arch #3, what are:
a) bones/cartilage it forms
b) nerves it forms
c) pouch
d) cleft
a) greater horn/inferior body of hyoid
b) CN IX
c) DORSAL - inferior parathyroid glands
VENTRAL - thymus
d) none
For pharyngeal arch #4 & 6, what are:
a) bones/cartilage it forms
b) nerves it forms
c) pouch
d) cleft
a) thyroid, cricoid, arytenoid cartilage
CN 4 b) superior laryngeal N
CN 6 b) recurrent laryngeal N
c) CN4 ventral ultimo pharyngeal body
CN4 dorsal superior parathyroid gland
d) none
note: Ultimopharyngeal body => C cells => calcitonin
For pharyngeal arch #5, what are:
a) bones/cartilage it forms
b) nerves it forms
c) pouch
d) cleft
trick question! It doesn’t form anything!!!
nothing for a, b, c, d
what are the 3 major roles of the vestibular system?
- generate eye movements to compensate for head movements
- adjust posture relative to head position
- mediate awareness of movement
In the vestibular system, which afferents and efferents are responsible for generating eye movements that compensate for head movements?
○ Afferent: CN VIII
○ Efferent: reticular formation, CN nuclei (abducens, oculomotor, trochlear)
In the vestibular system, which afferents and efferents are responsible for adjusting posture relative to position of the head?
○ Afferent: CN VIII
○ Efferent: cerebellum and SC
In the vestibular system, which afferents and efferents are responsible for mediating awareness of movement?
○ Afferent: CN VIII
○ Efferent: thalamus to cortex
In detail, tell me how the kinetic layrinths detect head rotational acceleration?
○ Contralateral lateral ducts work in concert (ex: contralateral anterior work with posterior)
○ Cristae ampullaris lie in each duct and respond to the shifting of endolymph
–> Shifts of the culpa move the stereocilia of the hair cells and stimulate transduction
–>Stereocilia deflection => open ion channels => K+ influx => Ca2+ influx => glutamate released
Tell me how the static layrinths detect linear acceleration? moreso, tell me the static labyrinths and which type of motion they detect
-Saccule = vertical motion
-Utricle = horizontal motion
-Together = otolith organs
Macula: area containing hair cells
Otoconia: calcium carbonate substance which moves the hair cells in order to transduce
What are the 3 tracts that make up the vestibular system/pathway?
- medial vestibulospinal tract
- lateral vestibulospinal tract
- vestibulocerebellar tract
For the medial vestibulospinal tract, tell me:
1. what function(s) does it do?
2. what reflex is associated with it?
3. where do the signals go/travel?
- Stabilizes head position when walking AND coordinates eyes and head movement
- Vestibulocollic reflex
- Descends MLF - bilateral