Somatosensation Flashcards

1
Q

What senses does somatosensation consist of?

A

touch, temperature, pain and proprioception

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2
Q

Where are the cell bodies of the primary sensory afferent neurons held?

A

the dorsal root ganglia

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3
Q

What is the polarity of the cell body?

A

pseudounipolar

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4
Q

What is the trigeminal ganglia?

A

the neuron that innervates the head and neck and projects centrally to the trigeminal nucleus

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5
Q

What is the nodose ganglia?

A

also known as the inferior vagal projects to the floor of the fourth ventricle and innervates the viscera via the vagus nerve

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6
Q

What are the sensory receptive properties?

A

modality, threshold, adaptation rate, conduction velocity and site of termination

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7
Q

What is modality?

A

the type of stimulus adequate for transducing a response i.e. light is usually the adequate stimulus for your eyes however putting pressure on them can cause the perception of light

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8
Q

What is the threshold?

A

low threshold units respond to low intensity and non-damaging stimuli
high threshold units respond to high but not low intensity stimuli which are potentially noxious and can be interpreted as painful if it reaches the higher centres of the brain

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9
Q

What is adaptation?

A

when a stimulus is maintained, the AP firing rate decreases as the the receptor adapts to the stimulus. can be rapid, slow, or very slow (v.rapid, rapid and slow) i.e. slow adaption might be if you have broken your leg and try to walk on it

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10
Q

What is the conduction velocity?

A

where primary sensory afferents differ greatly in thickness, myelination, conduction velocity and associated receptors

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11
Q

What is the site of termination?

A

the receptive field - ie. the region that when stimulated with an adequate stimulus will cause a response in the neuron

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12
Q

What are the sensory cutaneous receptors?

A

Mechanical contact - merkel discs, krause end bulbs, root hair plexus, meissners corpuscles, ruffini endings
Temperature/Pain - free nerve endings

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13
Q

How are the Meissners corpuscles and panincian corpuscles innervated?

A

Meissners - Ab - rapid adapting, stroking/flutter

Panician - Ab - very rapid adapting, vibration

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14
Q

How does the Pancinian Corpuscle work?

A

consists of a central nerve terminal which is surrounded by concentric, fluid-filled lamellae which when compressed sends a signal to the nerve terminal opening machano-sensitive ion channels
responds to maintained pressure by rapid adaptation making it good for sensing vibration

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15
Q

What are the comparable receptive fields of Meissners corpuscles and Panician Corpuscles on the hand?

A

Meissners - small receptive fields but lots of them

Pancinian - large receptive fields but only 2 main sensitivity spots

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16
Q

What is meant by two point discrimination?

A

the ability to discriminate between two points of stimulation can be small or large - upper arm 40mm fingers less than 1mm

17
Q

What is a dermatome?

A

the area of skin innervated by the left and right dorsal roots of a single segment

18
Q

How does the herpes zoster virus travel?

A

usually inflames one ganglia and therefore shows and inflammatory, blistery feeling along the dermatome that associates with it

19
Q

What is the somatosensory pathway to the brain?

A

the dorsal column medial lemniscal pathway

20
Q

What directions might the primary afferent neurons take to the brain?

A

immediately ascend via the dorsal column fasciculus gracilis or fasciculus cuneatus
synapse a second order neuron and ascend in the medial lemniscus to the ventral posterior nucleus of the thalamus