solubility Flashcards
1
Q
Equilibrium solubility
A
leave drug to dissolve for 24-48hrs
X(s) ——-> X(aq)
2
Q
Dissolution testing
A
test concentration over time
graph increases then plateaus
3
Q
intrinsic dissolution testing
A
flat compact unit
graph is linear
4
Q
what is supersaturation?
A
solubility becomes higher than equilibrium solubility
5
Q
bioavailability?
A
amount of drug that reaches systemic circulation
