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Oncology 15% > Solid Organ Cancer > Flashcards

Solid Organ Cancer Flashcards

1
Q

What are the 10 medications used for breast cancer?

HINT: Xeroxing An Imaged Kiss Verifies Needed Picture To Tally Love

A

Xeloda, Afinitor, Ibrance, Kisqali, Verzenio, Nerlynx, Piqray, Tykerb, Talzenna, Lynparza

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2
Q

What are the 10 medications used for lung cancer?

HINT: Acquired Another Lousy Xyphoid Zit, Giving Irenic Treatment To Vanish

A

Alecensa, Alunbrig, Lorbrena, Xalcori, Zycadia, Gilotrif, Iressa, Tagrisso, Tarceva, Vizimpro

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3
Q

What are the 6 medications used for melanoma?

HINT: Moisturizer The Mer Brands Zero Coverage

A

Mekinist, Tafinlar, Mektovi, Braftovi, Zelboraf, Cotellic

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4
Q

Which 2 medications are used for basal cell carcinoma?

HINT: hEdgehOg pathway inhibitors

A

Erivedge and Odonzo

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5
Q

Which 4 medications are used for thyroid cancer?

HINT: Cancer Causes Lumpy Neck

A

Caprelsa, Cometriq, Lenvima, Nexavar

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6
Q

Which 7 medications are used for renal cancer?

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A

Afinitor, Cabometyx, Inlyta, Lenvima, Nexavar, Sutent, Votrient

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7
Q

Which 4 medications are used for gynecologic cancers?

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A

Rubraca, Zejula, Lynparza, Lenvima (endometrial)

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8
Q

Which 4 medications are used for liver cancer?

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A

Cabometyx, Lenvima, Nexavar, Stivarga

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9
Q

Which 6 medications are used for prostate cancer?

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A

Erleada, Nubeqa, Xtandi, Zytiga, Yonza, Rubraca

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10
Q

Which 2 medications are used for pancreatic cancer?

HINT: Love To

A

Lynparza, Tarceva

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11
Q

Which 2 medications are used for CNS cancer?

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A

Gleostine, Temodar

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12
Q

Which 4 medications are used for colorectal cancer?

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A

Stivarga, Lonsurf (trifluridine and tipiracil), Braftovi, Xeloda

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13
Q

Which 3 medications are used for neuroendocrine tumors?

HINT: Affinity Supplies Xian

A

Afinitor, Sutent, Xermelo

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14
Q

Which medications are used for sarcomas?

HINT: Vote stupid sarcasically

A

Votrient-hair color changes

Stivarga and Sutent are for GISTs

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15
Q

What two medications is used for gastrointestinal stromal tumors (GISTs)?

HINT: Supporting Supplies

A

Stivarga, Sutent

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16
Q

Which 3 types of solid organ cancers are treated by Afinitor (everolimus)?

A

breast, renal and neuroendocrine

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17
Q

Which 2 types of solid organ cancers are treated by Cabometyx (cabozatinib)?

A

renal and liver

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18
Q

Which 4 types of solid organ cancers are treated by Lenvima (lenvatinib)?

A

thyroid, renal, liver and endometrial

19
Q

Which 3 types of solid organ cancers are treated by Lynparza (olaparib)?

A

breast, gynecologic and pancreatic

20
Q

Which 3 types of solid organ cancers are treated by Nexavar (sorafenib)?

A

thyroid, renal and liver

21
Q

Which 2 types of solid organ cancers are treated by Rubraca (rucaparib)?

A

gynecologic and prostate

22
Q

Which 3 types of solid organ cancers are treated by Stivarga (regorafenib)?

A

liver, colorectal and GIST

23
Q

Which 2 types of solid organ cancers are treated by Tarceva (erlotinib)?

A

lung and pancreatic

24
Q

Which 2 types of solid organ cancers are treated by Xeloda (capecitabine)?

A

breast and colorectal

25
Q

Which 6 mechanisms of action are used to treat breast cancer?

A
  • pyrimidine antimetabolite
  • mTOR inhibitor
  • CDK4/6 inhibitor
  • Tyrosine Kinase Inhibitor (TKI)
    • HER1, HER2, HER4
    • EGFR
  • PhosphatidyLinositol-3-Kinase (Pl3K) Inhibitor
  • Poly (ADP-ribose) polymerase (PARP) enzyme Inhibitor
26
Q

Which types of Tyrosine Kinase Inhibitors are used to treat lung cancer?

A
  • anaplastic lymphoma kinase inhibitor
  • EGFR inhibitor
27
Q

Which two mechanisms of action are used to fight skin cancer?

A
  • Mitogen-activated extracellular kinase (MEK) inhibitors
  • Protein kinase B-raf (BRAF) inhibitors
28
Q

Which two types of TKIs are used to treat thyroid cancers?

A

They are all VEGF inhibitors; Caprelsa is also a EGFR inhibitor.

29
Q

Which 2 mechanisms of action are used to treat renal cancer?

A
  • mTOR inhibitor
  • TKI; VEGF inhibitors (all generic names end in “nib”)
30
Q

What is the only mechanism of action currently used to treat liver cancer?

A

All four of the medications currently approved to treat liver cancer are TKIs, (VEGF inhibitors).

31
Q

Gynecologic cancers are treated with which type of medication?

A

Three of the meds approved for gynecologic cancers are PARP inhibitors and one is a TKI (VEGF inhibitor).

32
Q

Which 3 types of drugs are currently used to treat prostate cancer?

A
  • Androgen Receptor Inhibitor (3)
  • CYP17 inhibitors (2)
  • PARP inhibitor (1)
33
Q

Which 2 types of drugs are used to treat pancreatic cancer?

A
  • PARP inhibitor
  • TKI (EGFR inhibitor)
34
Q

Alkylating agents are used to treat which type of solid organ cancers?

A

CNS cancers

35
Q

5 different mechanisms of action are currently used to treat colorectal cancers. What are they?

A
  • TKI (VEGF inhibitor)
  • Thymidine-based nucleic acid
  • Phosphorylase inhibitor
  • BRAF inhibitor
  • Pyrimidine antimetabolite
36
Q

Each of the 3 drugs currently used to treat neuroendocrine tumors has a different mechanism of action. What are they?

A
  • mTOR inhibitor
  • TKI (VEGF inhibitor)
  • Tryptophan hydrolase inhibitor
37
Q

All sarcomas (soft tissue and GISTs) are currently treated by which type of medication?

A

TKI (VEGF inhibitors) are currently the only MOA approved to treat either soft tissue sarcomas or GISTs. There are 3.

  • Votrient for STS
  • Stivarga and Sutent for GISTs
38
Q

Which 2 types of solid organ cancers are treated with Braftovi?

A

Melanoma and colorectal cancer

39
Q

Which 2 types of solid organ cancers are treated with Votrient?

A

renal and soft tissue sarcoma

40
Q

Which of the drugs used to treat breast cancer do not interact with grapefruit?

A

Xeloda, Piqray, Talzenna and Lynparza

41
Q

Which of the drugs used to treat breast cancer are co-administered with Xeloda?

A
  • Nerlynx for advanced or metastatic HER2+
    • Xeloda 750mg/m2 BID on days 1-14 of 21
  • Tykerb for advanced or metastatic HER2+
    • Xeloda 1000mg/m2 BID on days 1-14 of 21
42
Q

PPIs should be avoided with which medications used to treat solid organ cancers?

A
  • Tagrisso
  • Vizimpro
  • Votrient
  • Nerlyx, separate from antacids by 3 hours
43
Q

Which of the drugs for solid organ cancers should be taken with food?

A
  • Xeloda
  • Ibrance capsules
  • Nerlynx
  • Piqray
  • Alecensa
  • Zycadia
  • Nubeqa
  • Lonsurf

Oncology 15% (3 decks)

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