Solid Organ Cancer Flashcards
What are the 10 medications used for breast cancer?
HINT: Xeroxing An Imaged Kiss Verifies Needed Picture To Tally Love
Xeloda, Afinitor, Ibrance, Kisqali, Verzenio, Nerlynx, Piqray, Tykerb, Talzenna, Lynparza
What are the 10 medications used for lung cancer?
HINT: Acquired Another Lousy Xyphoid Zit, Giving Irenic Treatment To Vanish
Alecensa, Alunbrig, Lorbrena, Xalcori, Zycadia, Gilotrif, Iressa, Tagrisso, Tarceva, Vizimpro
What are the 6 medications used for melanoma?
HINT: Moisturizer The Mer Brands Zero Coverage
Mekinist, Tafinlar, Mektovi, Braftovi, Zelboraf, Cotellic
Which 2 medications are used for basal cell carcinoma?
HINT: hEdgehOg pathway inhibitors
Erivedge and Odonzo
Which 4 medications are used for thyroid cancer?
HINT: Cancer Causes Lumpy Neck
Caprelsa, Cometriq, Lenvima, Nexavar
Which 7 medications are used for renal cancer?
HINT: Affinity Can Induce Leaking Not Supporting Volume
Afinitor, Cabometyx, Inlyta, Lenvima, Nexavar, Sutent, Votrient
Which 4 medications are used for gynecologic cancers?
HINT: Romantic Zest Love Lining
Rubraca, Zejula, Lynparza, Lenvima (endometrial)
Which 4 medications are used for liver cancer?
HINT: Cabaret Libations Nyx Sobriety
Cabometyx, Lenvima, Nexavar, Stivarga
Which 6 medications are used for prostate cancer?
HINT: Encumbered Nether Xylem Zips Your Rush
Erleada, Nubeqa, Xtandi, Zytiga, Yonza, Rubraca
Which 2 medications are used for pancreatic cancer?
HINT: Love To
Lynparza, Tarceva
Which 2 medications are used for CNS cancer?
HINT: Gifted Talented
Gleostine, Temodar
Which 4 medications are used for colorectal cancer?
HINT: Supporting Lovely Butt Xeroxes
Stivarga, Lonsurf (trifluridine and tipiracil), Braftovi, Xeloda
Which 3 medications are used for neuroendocrine tumors?
HINT: Affinity Supplies Xian
Afinitor, Sutent, Xermelo
Which medications are used for sarcomas?
HINT: Vote stupid sarcasically
Votrient-hair color changes
Stivarga and Sutent are for GISTs
What two medications is used for gastrointestinal stromal tumors (GISTs)?
HINT: Supporting Supplies
Stivarga, Sutent
Which 3 types of solid organ cancers are treated by Afinitor (everolimus)?
breast, renal and neuroendocrine
Which 2 types of solid organ cancers are treated by Cabometyx (cabozatinib)?
renal and liver
Which 4 types of solid organ cancers are treated by Lenvima (lenvatinib)?
thyroid, renal, liver and endometrial
Which 3 types of solid organ cancers are treated by Lynparza (olaparib)?
breast, gynecologic and pancreatic
Which 3 types of solid organ cancers are treated by Nexavar (sorafenib)?
thyroid, renal and liver
Which 2 types of solid organ cancers are treated by Rubraca (rucaparib)?
gynecologic and prostate
Which 3 types of solid organ cancers are treated by Stivarga (regorafenib)?
liver, colorectal and GIST
Which 2 types of solid organ cancers are treated by Tarceva (erlotinib)?
lung and pancreatic
Which 2 types of solid organ cancers are treated by Xeloda (capecitabine)?
breast and colorectal
Which 6 mechanisms of action are used to treat breast cancer?
- pyrimidine antimetabolite
- mTOR inhibitor
- CDK4/6 inhibitor
- Tyrosine Kinase Inhibitor (TKI)
- HER1, HER2, HER4
- EGFR
- PhosphatidyLinositol-3-Kinase (Pl3K) Inhibitor
- Poly (ADP-ribose) polymerase (PARP) enzyme Inhibitor
Which types of Tyrosine Kinase Inhibitors are used to treat lung cancer?
- anaplastic lymphoma kinase inhibitor
- EGFR inhibitor
Which two mechanisms of action are used to fight skin cancer?
- Mitogen-activated extracellular kinase (MEK) inhibitors
- Protein kinase B-raf (BRAF) inhibitors
Which two types of TKIs are used to treat thyroid cancers?
They are all VEGF inhibitors; Caprelsa is also a EGFR inhibitor.
Which 2 mechanisms of action are used to treat renal cancer?
- mTOR inhibitor
- TKI; VEGF inhibitors (all generic names end in “nib”)
What is the only mechanism of action currently used to treat liver cancer?
All four of the medications currently approved to treat liver cancer are TKIs, (VEGF inhibitors).
Gynecologic cancers are treated with which type of medication?
Three of the meds approved for gynecologic cancers are PARP inhibitors and one is a TKI (VEGF inhibitor).
Which 3 types of drugs are currently used to treat prostate cancer?
- Androgen Receptor Inhibitor (3)
- CYP17 inhibitors (2)
- PARP inhibitor (1)
Which 2 types of drugs are used to treat pancreatic cancer?
- PARP inhibitor
- TKI (EGFR inhibitor)
Alkylating agents are used to treat which type of solid organ cancers?
CNS cancers
5 different mechanisms of action are currently used to treat colorectal cancers. What are they?
- TKI (VEGF inhibitor)
- Thymidine-based nucleic acid
- Phosphorylase inhibitor
- BRAF inhibitor
- Pyrimidine antimetabolite
Each of the 3 drugs currently used to treat neuroendocrine tumors has a different mechanism of action. What are they?
- mTOR inhibitor
- TKI (VEGF inhibitor)
- Tryptophan hydrolase inhibitor
All sarcomas (soft tissue and GISTs) are currently treated by which type of medication?
TKI (VEGF inhibitors) are currently the only MOA approved to treat either soft tissue sarcomas or GISTs. There are 3.
- Votrient for STS
- Stivarga and Sutent for GISTs
Which 2 types of solid organ cancers are treated with Braftovi?
Melanoma and colorectal cancer
Which 2 types of solid organ cancers are treated with Votrient?
renal and soft tissue sarcoma
Which of the drugs used to treat breast cancer do not interact with grapefruit?
Xeloda, Piqray, Talzenna and Lynparza
Which of the drugs used to treat breast cancer are co-administered with Xeloda?
- Nerlynx for advanced or metastatic HER2+
- Xeloda 750mg/m2 BID on days 1-14 of 21
- Tykerb for advanced or metastatic HER2+
- Xeloda 1000mg/m2 BID on days 1-14 of 21
PPIs should be avoided with which medications used to treat solid organ cancers?
- Tagrisso
- Vizimpro
- Votrient
- Nerlyx, separate from antacids by 3 hours
Which of the drugs for solid organ cancers should be taken with food?
- Xeloda
- Ibrance capsules
- Nerlynx
- Piqray
- Alecensa
- Zycadia
- Nubeqa
- Lonsurf
