Sodium Balance Flashcards

1
Q

Hyponatremia - Value?

A

135

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2
Q

Hyponatremia - Types (2)

A
  1. Pseudo - Does not cause HypoOsmollalilty (Asymptomatic)

2. True - Cause HypoOsmollality (Symtpomatic or Asymptomatic)

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3
Q

Water in Body?

A

TBW - 60% of BW

  1. ICF - Intra Cellular Fluid 60%
  2. ECF - Extra Cellular Fluid 40%:
    1. Interstititum - 80% of ECF
    2. Plasma - 20% ECF
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4
Q

Plasma Osmollality Calculation

A

POsm = 2 x P[Na+] + [Glu]/18 + BUN/2.8

Normal - 275-290

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5
Q

Plasma Tonicity Calculation

A

PTonicity = Effective Posm = 2 x P [Na+] + [Glu]/18

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6
Q

Hyponatremia clinical signs

A
Asymptomatic
Symptomatic - Mostly Neurological:
1. nausea, malaise
2. headache
3. lethargy
4. irratability
5. supor
6. comma
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7
Q

Pseudohyponatremia - Ethologies (3)

A
  1. Hyperglicemia (HyperTonic)
  2. Hyperlipidemia (IsoTonic)
  3. HyperProteinemia (IsoTonic)
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8
Q

Sodium correction for HyperGlycemia?

A

1.4 for every 100 above 100mg/dl glucose

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9
Q

Pseudohyponatremia - Types (2)

A
  1. Isotonic - Hyperlipidemia + Hyperproteinemia

2. Hypertonic - Hyperglycemia / IV Manitol

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10
Q

True-Hyponatremia - Types (3):

A
  1. Hypovolemia - Decreased TBNa
  2. Hypervolemia - Increased TBNa
  3. Normovolemia - Normal TBNa
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11
Q

Hypovolemia - Decreased TBN - Casuses(2)?

A

Tachycardia, Hypotension

  1. Renal / Diuretics - Una>20meq/L (Disothiazide > Fusid )
  2. Extra renal - Skin / GIT - UNa<20meq/L
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12
Q

Hypovolemia - Decreased TBN - Clinics

A
  1. Hypotension
  2. Tachycardia
  3. Dry mucos
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13
Q

Hypovolemia - Decreased TBN - TX?

A
  1. Cause

2. Normal Saline - isotonic - 0.9%

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14
Q

Hypervolemia - Increased TBNa - Casuses (4)?

A
Clinics: Edema, Ascitis
1. CHF
2. Cirrhosis 
3. Nephrotic synd
UNa < 20meq/
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15
Q

True-Hyponatremia - Hypervolemia - Urinary Sodium level?

A

א”ס לב, צרוזיס : מתחת 20meq/L
תסמונת נפרוטית: מתחת 20meq/L
באיבוד בכליות: מעל 20meq/L

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16
Q

True-Hyponatremia - Hypervolemia - TX?

A
  1. Limit Water intake
  2. Limit Sodium intake
  3. Loop Diuretic
  4. Treat main cause (should be 1st)
17
Q

True-Hyponatremia - Normovolemia

Normal TBN

A
  1. Normal BP
  2. No Tachycardia
  3. No Edema/Ascitis

SIADH
Una>40meq/L
Uosmol>100mosmol/L

18
Q

True-Hyponatremia - Normovolemia

Normal TBN - Urinary Sodium?

A

U(na)>40meq/L

19
Q

True-Hyponatremia - Normovolemia

Normal TBN - Urinary Sodium?

A
  1. Find Cause

2. Water Limit

20
Q

When to use Hypertonic Saline?

A

Only for Symptomatic Hyponatremia

Max rate - 0.5mEq/L/h

21
Q

Na Deficit (Male) ?

A

0.6 X Body Weight X (120 – Current Na)

22
Q

Na Deficit (Female) ?

A

0.5 X Body Weight X (120 – Current Na)

23
Q

Hypovolemia - Decreased TBN - Clinics

A
  1. Hypotension
  2. Tachycardia
  3. Dry mucos
24
Q

Hypovolemia - Decreased TBN - TX?

A
  1. Cause

2. Normal Saline - isotonic - 0.9%

25
Q

Hypervolemia - Increased TBNa - Casuses (4)?

A
Clinics: Edema, Ascitis
1. CHF
2. Cirrhosis 
3. Nephrotic synd
UNa < 20meq/
26
Q

True-Hyponatremia - Hypervolemia - Urinary Sodium level?

A

א”ס לב, צרוזיס : מתחת 20meq/L
תסמונת נפרוטית: מתחת 20meq/L
באיבוד בכליות: מעל 20meq/L

27
Q

True-Hyponatremia - Hypervolemia - TX?

A
  1. Limit Water intake
  2. Limit Sodium intake
  3. Loop Diuretic
  4. Treat main cause (should be 1st)
28
Q

True-Hyponatremia - Normovolemia

Normal TBN

A
  1. Normal BP
  2. No Tachycardia
  3. No Edema/Ascitis

SIADH
Una>40meq/L
Uosmol>100mosmol/L

29
Q

True-Hyponatremia - Normovolemia

Normal TBN - Urinary Sodium?

A

U(na)>40meq/L

30
Q

True-Hyponatremia - Normovolemia

Normal TBN - Urinary Sodium?

A
  1. Find Cause

2. Water Limit

31
Q

When to use Hypertonic Saline?

A

Only for Symptomatic Hyponatremia

Max rate - 0.5mEq/L/h

32
Q

Na Deficit (Male) ?

A

0.6 X Body Weight X (120 – Current Na)

33
Q

Na Deficit (Female) ?

A

0.5 X Body Weight X (120 – Current Na)