Calcium and Phosphate balance

Question 1

Mediators (3)?

Answer 1

1. PTH
2. Vit D
3. FGF23

Question 2

Corrected [Ca]?

Answer 2

Measured total [Ca]+(0.8x(4.5-[alb])

Question 3

PTH effect on Calcium (3)?

Answer 3

1. Decreased urinary calcium excretion (Calcium reabsorption in DT)
2. Increased bone resorption
3. Increased intestinal Calcium absorption (mediated by increased renal production of Vit D)

Question 4

PTH & Phosphate?

Answer 4

PTH reduces proximal tubular phosphate reabsorption, resulting in enhanced excretion