Glumerular Disease

Question 1

Nephrotic syndrome - Clinics

Answer 1

1. Massive Proteinuira (>3.5 gm/day)
2. HypoAlbuminemia
3. Severe Edema
4. HyperLipidemia

Question 2

Nephrotic Range Proteinuria - Clinics

Answer 2

Massive protinuria without edema/HypoAlbuminemia

Question 3

Acute Nephritis - Clinics

Answer 3

1. Hematuria ( usually RBC CASTS )
2. Mild/moderate Proteinuria
3. Azotemia (elevated BUN and\or creatinine due to low GFR)
4. Hypertension (usually)

Question 4

Acute Glumerulo Nephritis - Diseases

Answer 4

1. Acute postinfection GN
   Diffuse Proliferative GN = Postinfectious GN
2. Lopus proliferative GN

Question 5

Nephrotic Syndrome -

Primary Diseases

Answer 5

1. MCD – Minimal Change Disease
2. FSGS – Focal Segmenal GlomeroloSclerosis
3. Membranous GN/Nephropathy
4. MPGN – Membrano Proliferative GN

Question 6

Nephrotic Symdrome - Seconday diseases

Answer 6

1. DM
2. Amiloid
3. lupus

Question 7

Rapidly Progressive GN = Crescentic GN

Answer 7

1. Pauci-immue – 90% ANCA positive
2. Immune complex (IF: granular IgG)
3. Anti GBM (IF: linear IgG)

Question 8

ANCA associated vasculitis

Answer 8

1. Microscopic polyangiitis
2. Wegener’s granulomatosis
3. Churg-Strauss disease