SOAG Flashcards
Without exception, all secondary
glaucomas arise due to
Abnormality in outflow
T/F: XFS is age-related
TRUE
XFS is characterized by deposition of ___ material throughout the body
Extracellular fibrillar (beta amyloid)
described as razor blades, not fluffy
Men or women: XFS more common
Women
T/F: LOXL1 is a useful screening tool for XFS
FALSE
Describe the latitude, climate, and solar impact on XFS
Higher latitude (upper US), colder climate, and more time outside —> RF
What is the most consistent and important Dx feature of XFS?
Deposits on ant surface of lens
Describe classic XFS pattern on lens (when dilated)
Central zone (relatively homogenous), intermediate clear zone, then peripheral (granular/patchy) layer
In XFS, why is phacodenesis and lens dislocation common?
Weak zonules
Features of XFS on iris
- XFM on iris sphincter (may be subtle)
- Pigment loss from iris sphincter
- Iris blood vessel abnormalities (eg rubeosis) **NVA is rare
What can be found on cornea in XFS?
Flakes of XFM on endo surface + increased CCT
Increased TM pigmentation is a prominent sign of XFS. Unlike PDS, the distribution of the pigment
tends to be …
Uneven, splotchy
How to diff between XFS and Capsular Delamination?
Capsular Delamination is associated with ___ due to ___.
CAT; heat exposure
T/F: POAG has a more severe clinical course and worse prognosis than XFG .
FALSE; XFG progression is worse than POAG
Target pressure for XFS
17
Why CAI CI’d w/ XFS?
Compromised endo
___ is the procedure of choice for XFG
Trabeculectomy
Classic triad of PDS:
- Corneal endo pigment (Krukenberg)
- Mid-peripheral transillumination defects
- Dense homogenous pigment of TM
PDS/PG occurs almost exclusively in ___ (race)
Caucasians
Flap Valve Effect
AH can pass from PC to AC but not back —> higher pressure in AC —> displaces iris posteriorly
Why does burnout phase of PG occur?
As lens gets larger and Miosis occurs, iris pulled away from zonules
T/F: IOP elevation in PDS is sue to pigment blockage
FALSE; phagocytosis of TM cells overload —> TM cells die —> meshwork collapses
T/F: Krukenerg pathognomonic of PDS
FALSE; but seen in 95% of PDS
Transillumination more obvious in ___ eyes
Light
Why is it important to record post-dilation IOP in PDS pts?
Acute IOP spikes can occur due to pigment cloud in AC