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Z. Glaucoma — Class Final > Drops > Flashcards

Drops Flashcards

1
Q

RED CAP

A

Cycloplegics/Dilation (e.g. atropine)

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2
Q

PINK/WHITE CAP

A

Anti-inflammatory (e.g. Lotemax)

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3
Q

TAN CAP

A

ANTIBIOTICS (eg Moxeza)

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4
Q

GRAY CAP

A

NSAIDS

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5
Q

GRAY CAP

A

NSAIDS

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6
Q

YELLOW CAP

A

Beta Blocker

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7
Q

LIGHT BLUE CAP

A

Selective Beta Blocker

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8
Q

GREEN CAP

A

Mitotic (eg Pilocarpine)

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9
Q

PURPLE CAP

A

Alpha agonist (eg Alphagan)

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10
Q

ORANGE CAP

A

CAIs (eg Azopt, Trusopt)

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11
Q

TEAL CAP

A

Prostaglandin

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12
Q

DARK BLUE CAP

A

COMBIGAN: Timolol (AA) + Brimonidine (BB)

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13
Q

SQUARE BOTTLE

A

Cosopt — Timolol (BB) + Dorzolamide/Trusopt (CAI)

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14
Q

MOA for Prostaglandin

A

Inc uveoscleral outflow

metalloproteinases break down collagen matrix

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15
Q

PGA is usually first-line therapy unless…

A
  1. HX of uveitis
  2. Complicated CAT
  3. Mac edema
  4. Hx of Herpes Simplex
  5. Unilateral TX
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16
Q

Peak effect of PGA occurs at…

A

4 weeks

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17
Q

Physical signs/side effects of PGA

A
  1. Iris darkening
  2. Eyelid pigmentation
  3. Prostaglandin Associated Periorbitopathy
  4. Hypertrichosis
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18
Q

Xalatan

A

Generic PGA 0.005%

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19
Q

Vyzulta

A

Latanoprostene — 0.024%
Dissociates into PGA and NO
PGA: inc UVO
NO: inc TMO

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20
Q

Travatan Z

A

Travoprost 0.004%
Preserved w/ SofZia (alternative to BAK)

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21
Q

Zioptan

A

Tafluprost 0.0015%
PF, single-vials

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22
Q

Xelpros

A

Latanoprost 0.005%
+ Michelle Microemulsion —> inc penetration

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23
Q

Lumigan

A

Bimatoprost 0.01%, 0.03%
Aka Latisse

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24
Q

Iyuzeh

A

PF Latanoprost

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25
Q

MOA Beta Blockers

A

Dec AH production

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26
Q

T/F: systemic BB increases effect of topical BB

A

FALSE

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27
Q

There are more ___ receptors in the CB than ___

(B1 vs B2)

A

More B2 than B1

28
Q

T/F: Those with darker irises (eg AA pts) may require larger dose of BB

29
Q

Association b/w BB and Myasthenia Gravis?

A

Topical BB assc w/ development/exacerbation of MG

30
Q

What BB is best used asthmatic pts?

31
Q

MOA for Alpha 2 Agonists?

A
  1. Dec AH prod
  2. Inc UVO
32
Q

Use for Aproclonidine

A

Acute IOP decrease (due to tachyphylaxis)

33
Q

The only Cat B GLC agent due to its neuro-protective factor

A

Alpha Agonist

34
Q

What drugs are CI’d with AA?

A

MAO inhibitors or tricyclic antidepressants

35
Q

Lumify

A

Brimonidine 0.025%

36
Q

Why are children under 2 not to take AA?

A

CNS depression: apnea, bradycardia, hypotension

37
Q

SE’s of AA? (8)

A
  • Xerostomia (dry mouth)
  • Lethargy
  • CNS depression
  • Toxicity/Type 4 Rxn (follicular)
  • Irritated eyes/skin
  • HA’s
  • Burn/sting
  • Miosis
38
Q

MOA of CAI?

A

Dec AH prod

39
Q

Azopt

A

Brinzolamide (suspension)

40
Q

Which stings less: Azopt vs Trusopt?

A

Azopt stings less

41
Q

For who would Methazolamide be the best choice (over other drugs in its same class)?

A

Pts w/ renal issues/metabolic acidosis

Least effective but least side effects

42
Q

Which CAI comes with an ER option?

A

Diamox (Azetazolamide)

“Diamox Sequel”

43
Q

T/F: topical CAIs further increase IOP lowering effect of oral CAI

44
Q

Why should CAIs be used w/ caution in Fuch’s pts?

A

Decrease is CA metabolism —> endothelium decomp —> guttata

45
Q

CAIs are ____-based

46
Q

Which class of meds are associated with bitter metallic taste?

47
Q

Which class of meds are associated with numbness in extremities?

48
Q

Biggest downside to Rho Kinase Inhibitors?

49
Q

Which class of meds are associated with corneal verticillata?

A

Rho Kinase Inhibitors

50
Q

MOA of RockI?

A

Inc TMO

some studies suggest dec episcleral venous pressure —> dec AH prod

51
Q

Which class of meds are associated with brow ache?

A

Pilocarpine

52
Q

For what type of GLC is pilocarpine most common?

A

Narrow Angle

53
Q

MOA of parasympathomimetic agents?

A

Contracts longitudinal CM —> inc TMO

54
Q

Other than pilocarpine, what other drug is in the same class?

55
Q

What can decrease the effectivity of hyperosmotic agents?

A

Defective BAB

56
Q

T/F: hyperosmotic agents known to taste like fruit juice

A

FALSE; often mixed with fruit juice due to tasting bad

57
Q

Wha hyperosmotic agent is used for Diabetic pts?

A

Isosorbide

58
Q

What are the potential SEs of a SM pt taking a hyperosmotic agent (eg oral glycerol)?

A

Ketoacidosis or Hyperglycemia

59
Q

Which class of meds are associated with subarachnoid or subdural hemorrhage?

A

Hyperosmotic agent

60
Q

Timeline of oral glycerol use

A

Onset: 10 min
Peaks: 1 hr
Lasts: 4-5 hrs

61
Q

Dosage for Hyperosmotic agent

A

1.0-1.5 g (or 2-3 ml) /kg body weight

62
Q

Pts w/ kidney issues should avoid what (2) GLC drugs?

A

CAI and hyperosmotics

63
Q

Cosopt

A

Timolol + Dorzolamide

64
Q

COMBIGAN

A

Timolol + Brimonidine

65
Q

Simbrinza

A

Brinzolamide + Brimonidine

66
Q

Rocklatan

A

Latanoprost + Netarsudil

PGA + ROCK

Z. Glaucoma — Class Final (8 decks)

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