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Z. Glaucoma — Class Final > Drops > Flashcards

Drops Flashcards

1
Q

RED CAP

A

Cycloplegics/Dilation (e.g. atropine)

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2
Q

PINK/WHITE CAP

A

Anti-inflammatory (e.g. Lotemax)

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3
Q

TAN CAP

A

ANTIBIOTICS (eg Moxeza)

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4
Q

GRAY CAP

A

NSAIDS

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5
Q

GRAY CAP

A

NSAIDS

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6
Q

YELLOW CAP

A

Beta Blocker

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7
Q

LIGHT BLUE CAP

A

Selective Beta Blocker

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8
Q

GREEN CAP

A

Mitotic (eg Pilocarpine)

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9
Q

PURPLE CAP

A

Alpha agonist (eg Alphagan)

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10
Q

ORANGE CAP

A

CAIs (eg Azopt, Trusopt)

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11
Q

TEAL CAP

A

Prostaglandin

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12
Q

DARK BLUE CAP

A

COMBIGAN: Timolol (AA) + Brimonidine (BB)

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13
Q

SQUARE BOTTLE

A

Cosopt — Timolol (BB) + Dorzolamide/Trusopt (CAI)

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14
Q

MOA for Prostaglandin

A

Inc uveoscleral outflow

metalloproteinases break down collagen matrix

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15
Q

PGA is usually first-line therapy unless…

A
  1. HX of uveitis
  2. Complicated CAT
  3. Mac edema
  4. Hx of Herpes Simplex
  5. Unilateral TX
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16
Q

Peak effect of PGA occurs at…

A

4 weeks

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17
Q

Physical signs/side effects of PGA

A
  1. Iris darkening
  2. Eyelid pigmentation
  3. Prostaglandin Associated Periorbitopathy
  4. Hypertrichosis
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18
Q

Xalatan

A

Generic PGA 0.005%

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19
Q

Vyzulta

A

Latanoprostene — 0.024%
Dissociates into PGA and NO
PGA: inc UVO
NO: inc TMO

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20
Q

Travatan Z

A

Travoprost 0.004%
Preserved w/ SofZia (alternative to BAK)

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21
Q

Zioptan

A

Tafluprost 0.0015%
PF, single-vials

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22
Q

Xelpros

A

Latanoprost 0.005%
+ Michelle Microemulsion —> inc penetration

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23
Q

Lumigan

A

Bimatoprost 0.01%, 0.03%
Aka Latisse

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24
Q

Iyuzeh

A

PF Latanoprost

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25
MOA Beta Blockers
Dec AH production
26
T/F: systemic BB increases effect of topical BB
FALSE
27
There are more ___ receptors in the CB than ___ (B1 vs B2)
More B2 than B1
28
T/F: Those with darker irises (eg AA pts) may require larger dose of BB
TRUE
29
Association b/w BB and Myasthenia Gravis?
Topical BB assc w/ development/exacerbation of MG
30
What BB is best used asthmatic pts?
Betaxolol
31
MOA for Alpha 2 Agonists?
1. Dec AH prod 2. Inc UVO
32
Use for Aproclonidine
Acute IOP decrease (due to *tachyphylaxis*)
33
The only Cat B GLC agent due to its neuro-protective factor
Alpha Agonist
34
What drugs are CI’d with AA?
MAO inhibitors or tricyclic antidepressants
35
Lumify
Brimonidine 0.025%
36
Why are children under 2 not to take AA?
CNS depression: apnea, bradycardia, hypotension
37
SE’s of AA? (8)
- Xerostomia (dry mouth) - Lethargy - CNS depression - Toxicity/Type 4 Rxn (follicular) - Irritated eyes/skin - HA’s - Burn/sting - Miosis
38
MOA of CAI?
Dec AH prod
39
Azopt
Brinzolamide (suspension)
40
Which stings less: Azopt vs Trusopt?
Azopt stings less
41
For who would Methazolamide be the best choice (over other drugs in its same class)?
Pts w/ renal issues/metabolic acidosis Least effective but least side effects
42
Which CAI comes with an ER option?
Diamox (Azetazolamide) “Diamox Sequel”
43
T/F: topical CAIs further increase IOP lowering effect of oral CAI
FALSE
44
Why should CAIs be used w/ caution in Fuch’s pts?
Decrease is CA metabolism —> endothelium decomp —> guttata
45
CAIs are ____-based
SULFA
46
Which class of meds are associated with **bitter metallic taste**?
CAIs
47
Which class of meds are associated with numbness in extremities?
CAIs
48
Biggest downside to Rho Kinase Inhibitors?
**$$$**
49
Which class of meds are associated with **corneal verticillata**?
Rho Kinase Inhibitors
50
MOA of RockI?
Inc TMO *some studies suggest dec episcleral venous pressure —> dec AH prod*
51
Which class of meds are associated with **brow ache**?
Pilocarpine
52
For what type of GLC is pilocarpine most common?
Narrow Angle
53
MOA of parasympathomimetic agents?
Contracts longitudinal CM —> inc TMO
54
Other than pilocarpine, what other drug is in the same class?
Carbachol
55
What can decrease the effectivity of hyperosmotic agents?
Defective BAB
56
T/F: hyperosmotic agents known to taste like fruit juice
FALSE; often mixed with fruit juice due to tasting bad
57
Wha hyperosmotic agent is used for Diabetic pts?
Isosorbide
58
What are the potential SEs of a SM pt taking a hyperosmotic agent (eg oral glycerol)?
Ketoacidosis or Hyperglycemia
59
Which class of meds are associated with **subarachnoid or subdural hemorrhage**?
Hyperosmotic agent
60
Timeline of oral glycerol use
Onset: 10 min Peaks: 1 hr Lasts: 4-5 hrs
61
Dosage for Hyperosmotic agent
1.0-1.5 g (or 2-3 ml) /kg body weight
62
Pts w/ kidney issues should avoid what (2) GLC drugs?
CAI and hyperosmotics
63
Cosopt
Timolol + Dorzolamide
64
COMBIGAN
Timolol + Brimonidine
65
Simbrinza
Brinzolamide + Brimonidine
66
Rocklatan
Latanoprost + Netarsudil PGA + ROCK

Z. Glaucoma — Class Final (8 decks)

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